注意缺陷多动障碍(ADHD)对社会功能和卫生保健结果的长期影响

IF 3.7 2区 医学 Q1 PSYCHIATRY Journal of psychiatric research Pub Date : 2025-02-01 DOI:10.1016/j.jpsychires.2025.01.016
Poul Jennum , Anne Virring Sørensen , Lone Baandrup , Michael Ibsen , Rikke Ibsen , Jakob Kjellberg
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引用次数: 0

摘要

关于注意缺陷多动障碍(ADHD)治疗对教育和社会结果的长期影响的研究是有限的。本研究旨在评估ADHD患者的长期社会功能结局以及ADHD药物治疗的潜在影响。方法:我们使用1995年至2016年的国家患者登记数据来识别诊断为ADHD的患者和收集ADHD药物的患者。符合条件的患者年龄在30岁以下或在2005年至2016年期间达到30岁,确保至少10年的观察期。采用病例对照设计,根据年龄、性别和指数年的居住城市,将ADHD患者与一般人群按1:4的比例进行匹配。结果:与对照组相比,ADHD患者经历了大量的社会经济困难,表现为直接医疗费用增加,精神合并症发生率更高,以及更多的联合用药。没有发现坚持ADHD药物治疗与30岁时完成教育之间的联系。坚持服用ADHD药物似乎会对30岁时的就业状况产生负面影响,这与精神合并症的严重程度相混淆。结论:尽管有现有的治疗方法,ADHD患者在实现社会功能方面仍然滞后。需要进一步的研究来更好地了解如何支持ADHD患者,以缩小健康和社会经济地位方面的差距。
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Long-term effects of attention deficit hyperactivity disorder (ADHD) on social functioning and health care outcomes

Introduction

Research on the long-term effects of treatment for attention deficit hyperactivity disorder (ADHD) on educational and social outcomes is limited. This study aims to evaluate long-term social functioning outcomes in patients with ADHD and the potential effects of pharmacological treatment for ADHD.

Methods

We used National Patient Registry data from 1995 to 2016 to identify patients diagnosed with ADHD and those collecting ADHD medication. Eligible patients were under 30 years old or had reached 30 between 2005 and 2016, ensuring a minimum 10-year observation period. A case-control design was applied, matching ADHD patients in a ratio of 1:4 with the general population based on age, sex, and residential municipality at the index year.

Results

Patients with ADHD experienced substantial socioeconomic difficulties, indicated by increased direct health care costs, higher rates of psychiatric comorbidities, and greater co-medication use compared with controls. No association was found between adherence to ADHD medication and completion of education at age 30 years. Adherence to ADHD medication appeared to negatively impact employment status at age 30, confounded by the severity of psychiatric comorbidity.

Conclusions

Despite available treatments, patients with ADHD lag in achieving social functioning outcomes. Further research is needed to better understand how to support patients with ADHD in order to close the gaps in health and socioeconomic status.
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来源期刊
Journal of psychiatric research
Journal of psychiatric research 医学-精神病学
CiteScore
7.30
自引率
2.10%
发文量
622
审稿时长
130 days
期刊介绍: Founded in 1961 to report on the latest work in psychiatry and cognate disciplines, the Journal of Psychiatric Research is dedicated to innovative and timely studies of four important areas of research: (1) clinical studies of all disciplines relating to psychiatric illness, as well as normal human behaviour, including biochemical, physiological, genetic, environmental, social, psychological and epidemiological factors; (2) basic studies pertaining to psychiatry in such fields as neuropsychopharmacology, neuroendocrinology, electrophysiology, genetics, experimental psychology and epidemiology; (3) the growing application of clinical laboratory techniques in psychiatry, including imagery and spectroscopy of the brain, molecular biology and computer sciences;
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