Mamoun W Sweileh, Ayman Dawoud, Razan Malhis, Banan M Aiesh
{"title":"发展中国家急性髓性白血病患者弥散性头孢霉感染1例。","authors":"Mamoun W Sweileh, Ayman Dawoud, Razan Malhis, Banan M Aiesh","doi":"10.1093/omcr/omae176","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong><i>Saprochaete capitata</i> may cause fatal infections in immunocompromised patients. This is the first case report of invasive <i>Saprochaete capitate</i> infection at an academic-tertiary care center in Palestine.</p><p><strong>Case presentation: </strong>We report a 36-year-old woman who presented with fever and severe neutropenia and was found to have AML/Non M3. While receiving her initial chemotherapy treatment, she encountered a rare fungal infection (<i>Saprochaete capitata</i>) that spread throughout her lungs, stomach, spleen, liver, and kidneys, presenting difficulties in both diagnosing and treatment. In addition to being treated with both voriconazole and amphotericin B, the patient underwent surgery to remove the infection source, resulting in a cure.</p><p><strong>Conclusion: </strong>In immunocompromised patients, <i>Saprochaete <i>capitata</i></i> infection is frequently overlooked. It is essential to give antifungal combinations and to control the source of infection to enhance the outcome for patients.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 1","pages":"omae176"},"PeriodicalIF":0.5000,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748307/pdf/","citationCount":"0","resultStr":"{\"title\":\"Disseminated fungal infection with <i>Saprochaete capitata</i> in acute myeloid leukemia patient: a case report from a developing country.\",\"authors\":\"Mamoun W Sweileh, Ayman Dawoud, Razan Malhis, Banan M Aiesh\",\"doi\":\"10.1093/omcr/omae176\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong><i>Saprochaete capitata</i> may cause fatal infections in immunocompromised patients. This is the first case report of invasive <i>Saprochaete capitate</i> infection at an academic-tertiary care center in Palestine.</p><p><strong>Case presentation: </strong>We report a 36-year-old woman who presented with fever and severe neutropenia and was found to have AML/Non M3. While receiving her initial chemotherapy treatment, she encountered a rare fungal infection (<i>Saprochaete capitata</i>) that spread throughout her lungs, stomach, spleen, liver, and kidneys, presenting difficulties in both diagnosing and treatment. In addition to being treated with both voriconazole and amphotericin B, the patient underwent surgery to remove the infection source, resulting in a cure.</p><p><strong>Conclusion: </strong>In immunocompromised patients, <i>Saprochaete <i>capitata</i></i> infection is frequently overlooked. It is essential to give antifungal combinations and to control the source of infection to enhance the outcome for patients.</p>\",\"PeriodicalId\":45318,\"journal\":{\"name\":\"Oxford Medical Case Reports\",\"volume\":\"2025 1\",\"pages\":\"omae176\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-01-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748307/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oxford Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/omcr/omae176\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/omcr/omae176","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Disseminated fungal infection with Saprochaete capitata in acute myeloid leukemia patient: a case report from a developing country.
Background: Saprochaete capitata may cause fatal infections in immunocompromised patients. This is the first case report of invasive Saprochaete capitate infection at an academic-tertiary care center in Palestine.
Case presentation: We report a 36-year-old woman who presented with fever and severe neutropenia and was found to have AML/Non M3. While receiving her initial chemotherapy treatment, she encountered a rare fungal infection (Saprochaete capitata) that spread throughout her lungs, stomach, spleen, liver, and kidneys, presenting difficulties in both diagnosing and treatment. In addition to being treated with both voriconazole and amphotericin B, the patient underwent surgery to remove the infection source, resulting in a cure.
Conclusion: In immunocompromised patients, Saprochaete capitata infection is frequently overlooked. It is essential to give antifungal combinations and to control the source of infection to enhance the outcome for patients.
期刊介绍:
Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.