无乳糖饮食作为治疗前低位切除综合征的策略:一个病例系列。

IF 0.4 Q4 SURGERY Journal of Surgical Case Reports Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI:10.1093/jscr/rjae850
Da W Thong, Mary Theophilus
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引用次数: 0

摘要

低位前切除术综合征(LARS)是保留括约肌直肠手术后的一个具有挑战性的并发症,其特征是肠功能障碍,如急迫性、频率和尿失禁。本病例系列研究乳糖不耐症在加剧LARS症状中的潜在作用。3例直肠切除术后发生LARS的患者,尽管采用填充剂、物理治疗和洛哌丁胺进行常规治疗,但症状仍持续存在。然而,在从他们的饮食中剔除牛奶后,这三个人的症状都有了显著改善,这反映在他们的LARS评分降低上。这些发现表明乳糖不耐症(包括可能的迟发性乳糖不耐症)与LARS症状之间存在潜在联系。这项研究强调了饮食调整的有效性,特别是乳糖消除,作为一种简单而非侵入性的治疗LARS的策略。研究结果还支持了对牛奶替代品进行膳食筛选和推荐以加强临床护理的必要性。需要进一步的研究来验证这些观察结果并完善治疗策略。
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Lactose free diet as therapeutic strategy in low anterior resection syndrome: a case series.

Low anterior resection syndrome (LARS) is a challenging complication following sphincter-preserving rectal surgery, characterized by bowel dysfunctions such as urgency, frequency, and incontinence. This case series investigates the potential role of lactose intolerance in exacerbating LARS symptoms. Three patients who developed LARS after rectal resections showed persistent symptoms despite conventional management with bulking agents, physiotherapy, and loperamide. However, all three experienced significant improvement in symptomatology, reflected by reductions in their LARS scores, after eliminating cow's milk from their diets. These findings suggest a potential link between lactose intolerance, including possible late-onset forms, and LARS symptoms. This study highlights the effectiveness of dietary modifications, particularly lactose elimination, as a simple and non-invasive strategy for managing LARS. The findings also support the need for dietary screening processes and recommendations for milk substitutes to enhance clinical care. Further research is necessary to validate these observations and refine therapeutic strategies.

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来源期刊
CiteScore
0.70
自引率
0.00%
发文量
559
审稿时长
11 weeks
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