转移性乳腺癌的治疗策略和前景。

IF 9.6 1区 医学 Q1 ONCOLOGY Cancer treatment reviews Pub Date : 2025-02-01 DOI:10.1016/j.ctrv.2025.102885
Peilin Dai , Tianyi Song , Junzhi Liu , Zuer He , Xiaoli Wang , Ran Hu , Jiqiao Yang
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引用次数: 0

摘要

化生性乳腺癌是一种罕见且异质性的乳腺癌亚型,预后较差。其独特的生物学行为和形态特征有助于抵抗标准治疗方案。迄今为止,对于转移性乳腺癌的最佳治疗策略仍有待探索。在此,我们回顾了关于转移性乳腺癌治疗的文献,总结了目前的局部和全身治疗方法,并根据其病理和分子特征讨论了潜在的治疗靶点和新的治疗策略。靶向治疗和免疫治疗可能提供更个性化的治疗选择,有可能改善这种疾病的预后。
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Therapeutic strategies and landscape of metaplastic breast cancer
Metaplastic breast cancer is a rare and heterogeneous subtype of breast cancer, associated with a poor prognosis. Its distinct biological behavior and morphological features contribute to resistance to standard treatment regimens. Hitherto, the optimal therapeutic strategy for metaplastic breast cancer remains underexplored. Herein, we review the literature on the treatment of metaplastic breast cancer, summarizing current local and systemic therapies, and discuss potential therapeutic targets and novel strategies based on its pathological and molecular characteristics. Targeted therapy and immunotherapy may provide more personalized treatment options, with the potential to improve the prognosis of this disease.
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来源期刊
Cancer treatment reviews
Cancer treatment reviews 医学-肿瘤学
CiteScore
21.40
自引率
0.80%
发文量
109
审稿时长
13 days
期刊介绍: Cancer Treatment Reviews Journal Overview: International journal focused on developments in cancer treatment research Publishes state-of-the-art, authoritative reviews to keep clinicians and researchers informed Regular Sections in Each Issue: Comments on Controversy Tumor Reviews Anti-tumor Treatments New Drugs Complications of Treatment General and Supportive Care Laboratory/Clinic Interface Submission and Editorial System: Online submission and editorial system for Cancer Treatment Reviews
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