Achim Fieß, Sandra Gißler, Stephanie Grabitz, Philipp S Wild, Karl J Lackner, Manfred E Beutel, Michael S Urschitz, Oliver Tüscher, Thomas Münzel, Jörn M Schattenberg, Stavros V Konstantinides, Norbert Pfeiffer, Alexander K Schuster
{"title":"短报告-出生体重与白内障或假性白内障无关-来自古腾堡健康研究的结果。","authors":"Achim Fieß, Sandra Gißler, Stephanie Grabitz, Philipp S Wild, Karl J Lackner, Manfred E Beutel, Michael S Urschitz, Oliver Tüscher, Thomas Münzel, Jörn M Schattenberg, Stavros V Konstantinides, Norbert Pfeiffer, Alexander K Schuster","doi":"10.2147/OPTH.S502181","DOIUrl":null,"url":null,"abstract":"<p><p>This study investigates the association between self-reported birth weight (BW) and the frequency of cataract and pseudophakia in a large population-based cohort in Germany, as part of the Gutenberg Health Study (GHS). Slit lamp examination and Scheimpflug imaging of 8205 participants, aged 35 to 74, were assessed and signs of cataract or pseudophakia analyzed. The research aimed to explore the correlation between fetal growth restriction and/or prematurity indicated by BW and the frequency of cataract and pseudophakia. In the univariable analysis, cataract was initially associated with low and high BW, but this association disappeared after adjusting for age, sex, examiner and cardiovascular risk factors. No association was found between low BW and pseudophakia or the frequency of cataract surgery within 5 years. The study reveals novel insights from a large population-based study specifically exploring this association.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"153-156"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745053/pdf/","citationCount":"0","resultStr":"{\"title\":\"Short Report - Birth Weight is Not Associated With Cataracts or Pseudophakia - Results from the Gutenberg Health Study.\",\"authors\":\"Achim Fieß, Sandra Gißler, Stephanie Grabitz, Philipp S Wild, Karl J Lackner, Manfred E Beutel, Michael S Urschitz, Oliver Tüscher, Thomas Münzel, Jörn M Schattenberg, Stavros V Konstantinides, Norbert Pfeiffer, Alexander K Schuster\",\"doi\":\"10.2147/OPTH.S502181\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study investigates the association between self-reported birth weight (BW) and the frequency of cataract and pseudophakia in a large population-based cohort in Germany, as part of the Gutenberg Health Study (GHS). Slit lamp examination and Scheimpflug imaging of 8205 participants, aged 35 to 74, were assessed and signs of cataract or pseudophakia analyzed. The research aimed to explore the correlation between fetal growth restriction and/or prematurity indicated by BW and the frequency of cataract and pseudophakia. In the univariable analysis, cataract was initially associated with low and high BW, but this association disappeared after adjusting for age, sex, examiner and cardiovascular risk factors. No association was found between low BW and pseudophakia or the frequency of cataract surgery within 5 years. The study reveals novel insights from a large population-based study specifically exploring this association.</p>\",\"PeriodicalId\":93945,\"journal\":{\"name\":\"Clinical ophthalmology (Auckland, N.Z.)\",\"volume\":\"19 \",\"pages\":\"153-156\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745053/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical ophthalmology (Auckland, N.Z.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2147/OPTH.S502181\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical ophthalmology (Auckland, N.Z.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/OPTH.S502181","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Short Report - Birth Weight is Not Associated With Cataracts or Pseudophakia - Results from the Gutenberg Health Study.
This study investigates the association between self-reported birth weight (BW) and the frequency of cataract and pseudophakia in a large population-based cohort in Germany, as part of the Gutenberg Health Study (GHS). Slit lamp examination and Scheimpflug imaging of 8205 participants, aged 35 to 74, were assessed and signs of cataract or pseudophakia analyzed. The research aimed to explore the correlation between fetal growth restriction and/or prematurity indicated by BW and the frequency of cataract and pseudophakia. In the univariable analysis, cataract was initially associated with low and high BW, but this association disappeared after adjusting for age, sex, examiner and cardiovascular risk factors. No association was found between low BW and pseudophakia or the frequency of cataract surgery within 5 years. The study reveals novel insights from a large population-based study specifically exploring this association.