以进行性核上性麻痹/皮质基底综合征为典型临床表现的患者中抗iglon5疾病的发生频率

IF 4.3 3区医学 Q2 CLINICAL NEUROLOGY Parkinsonism & related disorders Pub Date : 2025-06-01 Epub Date: 2025-01-15 DOI:10.1016/j.parkreldis.2025.107289

Yoya Ono , Hiroshi Takigawa , Akira Takekoshi , Nobuaki Yoshikura , Ikuko Aiba , Ritsuko Hanajima , Hisanori Kowa , Masato Kanazawa , Takahiko Tokuda , Aya Midori Tokumaru , Mitsuya Morita , Kazuko Hasegawa , Kenji Nakashima , Takeshi Ikeuchi , Akio Kimura , Takayoshi Shimohata , JALPAC Study Group

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引用次数: 0

摘要

对223例符合进行性核上性麻痹/皮质基底综合征（PSP/CBS）诊断标准的患者进行血清抗iglon5抗体检测，结果均为阴性。我们的研究表明，在典型的PSP/CBS患者中，抗iglon5疾病的频率非常罕见。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Frequency of anti-IgLON5 disease in patients with a typical clinical presentation of progressive supranuclear palsy/corticobasal syndrome

Serum anti-IgLON5 antibodies, which were tested in 223 patients meeting the diagnostic criteria for progressive supranuclear palsy/corticobasal syndrome (PSP/CBS), were negative in all patients. Our study suggests that the frequency of anti-IgLON5 disease is extremely rare in patients with typical presentation of PSP/CBS.

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来源期刊

Parkinsonism & related disorders 医学-临床神经学

CiteScore

6.20

自引率

4.90%

发文量

292

审稿时长

39 days

期刊介绍： Parkinsonism & Related Disorders publishes the results of basic and clinical research contributing to the understanding, diagnosis and treatment of all neurodegenerative syndromes in which Parkinsonism, Essential Tremor or related movement disorders may be a feature. Regular features will include: Review Articles, Point of View articles, Full-length Articles, Short Communications, Case Reports and Letter to the Editor.