Zhen Yang, Xiaoting Qi, Gaopeng Li, Na Wu, Bingwen Qi, Mengyang Yuan, Yaxin Wang, Guangling Hu, Qiaofang Yang
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引用次数: 0
摘要
心房颤动(AF)显著降低健康相关生活质量(HRQoL)。尽管运动干预治疗房颤得到了推广,但不同运动方式的有效性仍有待明确界定。本系统综述和网络荟萃分析旨在评估不同运动干预模式对房颤患者HRQoL的比较效果。方法:采用随机效应网络meta分析。我们在PubMed、Web of Science、Embase、Cochrane Library、Scopus等多个数据库以及CNKI、万方数据、VIP等中文数据库中进行了综合检索。这篇综述只纳入了随机对照试验(RCTs),这些试验调查了运动干预对af患者HRQoL的影响。结果:网络荟萃分析(NMA)纳入了12项研究,其中5项研究存在偏倚风险,1项研究存在高偏倚风险。对于房颤患者的总HRQoL,有氧运动和心脏康复(CR)的标准化平均差异分别为0.60 (95% CI: 0.02-1.13)和0.59 (95% CI: 0.20-0.99)。对于HRQoL的物理成分,CR最有效,其累积排名曲线(SUCRA)值最高,为77%。对于HRQoL的心理部分,高强度间歇训练(HIIT)的SUCRA值最高,达到90.7%。结论:有氧运动和CR均能有效改善房颤患者HRQoL的生理、心理维度以及总体HRQoL。然而,对于HRQoL的心理部分,HIIT被认为是最有效的干预。
The type of exercise most beneficial for quality of life in people with atrial fibrillation: a network meta-analysis.
Introduction: Atrial fibrillation (AF) significantly detracts from health-related quality of life (HRQoL). Despite the promotion of exercise interventions for managing AF, the effectiveness of different exercise modalities remains to be clearly defined. This systematic review and network meta-analysis aims to evaluate the comparative effectiveness of various modes of exercise interventions on HRQoL in AF patients.
Methods: A random-effect network meta-analysis was performed. We conducted comprehensive searches across multiple databases, including PubMed, Web of Science, Embase, Cochrane Library, Scopus, and Chinese databases such as CNKI, WanFang Data, and VIP. The review included only randomized controlled trials (RCTs) that investigated the effects of exercise interventions on HRQoL among individuals diagnosed with AF.
Results: The network meta-analysis (NMA) incorporated 12 studies, of which five presented some concerns regarding risk of bias and one exhibited a high risk of bias. For total HRQoL in AF patients, aerobic exercise, and cardiac rehabilitation (CR) yielded standardised mean differences of 0.60 (95% CI: 0.02-1.13) and 0.59 (95% CI: 0.20-0.99), respectively. For the physical component of HRQoL, CR was most efficacious, demonstrating the highest Surface Under the Cumulative RAnking curve (SUCRA) value of 77%. For the mental component of HRQoL, high-intensity interval training (HIIT) was superior, with the highest SUCRA value of 90.7%.
Conclusions: Both aerobic exercise and CR effectively improve the physical and mental dimensions of HRQoL as well as overall HRQoL in patients with AF. However, for the mental component of HRQoL, HIIT was identified as the most effective intervention.
期刊介绍:
Frontiers? Which frontiers? Where exactly are the frontiers of cardiovascular medicine? And who should be defining these frontiers?
At Frontiers in Cardiovascular Medicine we believe it is worth being curious to foresee and explore beyond the current frontiers. In other words, we would like, through the articles published by our community journal Frontiers in Cardiovascular Medicine, to anticipate the future of cardiovascular medicine, and thus better prevent cardiovascular disorders and improve therapeutic options and outcomes of our patients.