A型主动脉夹层主动脉弓的处理:更换,AMDS修复,还是留待日后?

IF 2.3 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiovascular Development and Disease Pub Date : 2025-01-12 DOI:10.3390/jcdd12010023
Ryaan El-Andari, Michael C Moon
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引用次数: 0

摘要

目的:急性A型主动脉夹层(ATAAD)是一种危及生命的疾病,需要紧急手术干预。ATAAD有许多手术入路,但关于ATAAD患者的最佳弓干预仍存在争议。主动脉弓干预:ATAAD修复的方法包括血弓修复或扩展弓修复,包括使用混合支架植入的血弓,如AMDS混合假体,全弓置换(TAR),以及使用象鼻和冷冻象鼻。虽然每种手术的适应症都存在,如弓的入口撕裂、弓状动脉瘤、用于TAR和灌注不良的头血管通信,以及用于AMDS和冷冻象鼻的Debakey I型主动脉夹层的远端吻合口新入口撕裂的风险降低,但最佳干预取决于许多因素。外科医生和中心的经验、资源可用性、患者风险和解剖结构都有助于决策过程。多年来,TAR的安全性有所提高,并已证明在许多情况下,其安全性可与疝修补术相媲美。TAR还可以预防不良重塑,并能有效治疗更远端疾病、弓撕裂、弓动脉瘤、分支血管受累或灌注不良。结论:治疗ATAAD有多种手术方法,允许外科医生根据个体患者和病理调整修复方法。TAR允许单次或分阶段修复广泛的病变,并可解决远端入口撕裂、动脉瘤弓和脑血管病变。在灌注不良的情况下,AMDS可以在许多情况下使用。ATAAD的治疗策略应始终包括对患者进行最佳手术,尽管在指征全弓手术但非主动脉外科医生不能安全操作的情况下,最安全的方法可能是先进行全弓手术,并在需要密切监测的情况下计划择期再行足弓手术。
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The Management of the Aortic Arch in Type A Aortic Dissection: Replace, Repair with the AMDS, or Leave for Another Day?

Objectives: Acute type A aortic dissection (ATAAD) is a life-threatening condition that requires emergent surgical intervention. Numerous surgical approaches exist for ATAAD, and controversy remains regarding the optimal arch interventions for ATAAD patients. Aortic Arch Interventions: Approaches to ATAAD repair include hemiarch repair or extended arch repairs, including the hemiarch with a hybrid stent implantation, such as the AMDS hybrid Prosthesis, total arch replacement (TAR), and the use of an elephant trunk and frozen elephant trunk. While indications for each procedure exist, such as entry tears in the arch, arch aneurysms, and head vessel communications for TAR and malperfusion and a reduced risk of distal anastomotic new entry tears in Debakey I aortic dissection for the AMDS and frozen elephant trunks, the optimal intervention depends on numerous factors. Surgeon and center experience, resource availability, patient risk, and anatomy all contribute to the decision-making process. TAR has improved in safety over the years and has been demonstrated to be comparable to the hemiarch repair in terms of safety in many settings. TAR may also prevent adverse remodeling and can effectively treat more distal diseases, the presence of arch tears, arch aneurysms, and branch vessel involvement or malperfusion.

Conclusions: Numerous surgical approaches exist to manage ATAAD, allowing for the surgeon to tailor the repair to the individual patient and pathology. TAR allows for single or staged repair of extensive pathologies and can address distal entry tears, the aneurysmal arch, and head vessel pathologies. In cases with malperfusion, an AMDS can be used in many cases. The management strategy for ATAAD should always involve performing the best surgery for the patient, although in cases where a total arch is indicated but cannot be performed safely by a non-aortic surgeon, the safest approach may be to perform a hemiarch initially and to plan for an elective arch reoperation in the case it is required following close surveillance.

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来源期刊
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.60
自引率
12.50%
发文量
381
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