优化颅底缺损修复:利用鼻中隔瓣的重复使用作为可靠材料。

IF 2.4 3区 医学 Q2 OTORHINOLARYNGOLOGY European Archives of Oto-Rhino-Laryngology Pub Date : 2025-04-01 Epub Date: 2025-01-25 DOI:10.1007/s00405-025-09213-2
Yu-Wen Huang, Wei-Hsin Wang, Ming-Ying Lan
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引用次数: 0

摘要

目的:颅底内镜手术的数量不断增加,需要探索更多的材料,以减少术后脑脊液(CSF)渗漏翻修或分期手术。本研究评估了鼻中隔瓣再使用在这种临床情况下的有效性。方法:回顾性分析在三级医疗中心接受nsf手术后经内镜鼻内入路(EEAs)进行翻修或二次颅底手术的患者。患者分为两组:一组使用可重复使用的nsf,另一组没有。分析了人口统计学、术中脑脊液泄漏、重建材料、术后发病率和完成缺损粘膜上皮化的时间。结果:该研究纳入了20例既往使用NSF的继发性EEAs患者。13例单独使用再生nsf或与内嵌脂肪或阔筋膜结合,其余7例使用其他材料。病理类型差异有统计学意义(p = 0.031)。重复使用的NSF在减少脑脊液泄漏方面显示出100%的成功率。粘膜上皮形成的平均时间为61天(SD = 34天)。结论:在翻修或分期手术中重复使用NSF是一种可靠的颅底修复技术,可以潜在地减少鼻腔发病率,并避免需要采集其他血管瓣。
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Optimizing skull base defect repair: leveraging the reused nasoseptal flap as a reliable material.

Purpose: The escalating number of endoscopic skull base procedures necessitates exploring additional materials to reduce postoperative cerebrospinal fluid (CSF) leaks in revision or staged surgeries. This study evaluates the effectiveness of reused nasoseptal flaps (NSFs) in such clinical scenarios.

Methods: A retrospective review was conducted on patients who previously underwent surgery involving NSFs and later had revision or secondary skull base surgeries via endoscopic endonasal approaches (EEAs) at a tertiary medical center. Patients were divided into two groups: one with reused NSFs and the other without. Demographics, intraoperative CSF leaks, reconstruction materials, postoperative morbidity, and time to complete mucoepithelialization of the defect were analyzed.

Results: The study included 20 patients with prior NSF usage who underwent secondary EEAs. Thirteen cases utilized reused NSFs alone or with inlay fat or fascia lata, while the remaining seven employed other materials. Pathology type disparity was significant (p = 0.031). Reused NSF demonstrated a 100% success rate in reducing CSF leaks. The average time for mucoepithelization was 61 days (SD = 34 days).

Conclusions: Reusing NSF in revision or staged surgeries is a reliable technique for skull base repair, potentially reducing nasal morbidity and obviating the need for harvesting other vascular flaps.

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来源期刊
CiteScore
5.30
自引率
7.70%
发文量
537
审稿时长
2-4 weeks
期刊介绍: Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.
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