原发性肝癌肉瘤1例,临床特点及预后因素回顾性分析。

IF 3.1 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Frontiers in Medicine Pub Date : 2025-01-10 eCollection Date: 2024-01-01 DOI:10.3389/fmed.2024.1470419
Zonglei Zhao, Tao Wang, Zhexuan Sun, Xuefeng Cao, Xingyuan Zhang
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摘要

原发性肝癌肉瘤(HCS)是一种极其罕见的恶性肿瘤,具有癌性和肉瘤性成分。很少有HCS的病例报道,特别是有足够的记录来描述影像学和病理特征,这使得HCS的诊断、治疗和预后对医生来说是一个重大挑战。在这里,我们报告一例HCS自发破裂为初始症状的77岁老年男性谁入院的右上腹部疼痛8 天。计算机断层增强扫描显示一肝内增强,密度混合,主要位于肝外的巨大增强影。我们通过剖腹手术进行了第四节肝切除术。术后病理结果显示HCS。病人恢复顺利,术后出院。然而,患者复发并在手术后5 个月死亡。该病例强调了在HCS病例中确定高危人群和个性化治疗策略的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Primary hepatic carcinosarcoma: a case report with insights from retrospective analysis of clinical characteristics and prognostic factors.

Primary hepatic carcinosarcoma (HCS) is an extremely rare malignant tumor with carcinomatous and sarcomatous elements. Few reported cases of HCS exist, especially with sufficient records to describe imaging and pathological features, making the diagnosis, treatment, and prognosis of HCS a significant challenge for physicians. Here, we report a case of HCS with spontaneous rupture as the initial symptom in a 77-year-old elderly male who was admitted with right upper abdominal pain for 8 days. The computed tomography enhancement scan revealed one intrahepatic enhancement with mixed density and a massive, enhanced shadow located mainly outside the liver. We performed a hepatectomy of segment 4 through a laparotomy. The postoperative pathology results demonstrated HCS. The patient recovered smoothly and was discharged after surgery. However, the patient experienced a recurrence and died 5 months after surgery. This case underscores the importance of identifying high-risk populations and personalized treatment strategies in HCS cases.

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来源期刊
Frontiers in Medicine
Frontiers in Medicine Medicine-General Medicine
CiteScore
5.10
自引率
5.10%
发文量
3710
审稿时长
12 weeks
期刊介绍: Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate - the use of patient-reported outcomes under real world conditions - the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines - the scientific bases for guidelines and decisions from regulatory authorities - access to medicinal products and medical devices worldwide - addressing the grand health challenges around the world
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