Synthesis of amino acids in intense laser-irradiated primary amine solutions†

Mechanical interatomic bond formation under ultrahigh pressure induced by laser-driven shock waves has been demonstrated for C–C, C–O, and O–O bonds. In this study, molecules generated in primary amine solutions irradiated with high-intensity lasers were identified. When methylamine or ethylamine was dissolved in methanol or ethanol, molecules likely formed through C–C or O–N bonds between the amine and alcohol were detected. Additionally, molecules thought to be formed through the bonding of amines were confirmed. In mixed solutions of amine and formic acid, the formation of amino acids, such as glycine and alanine, which are presumed to result from C–C bond formation, was also confirmed. The generation of these molecules is attributed to mechanical bond formation due to the ultrahigh pressure generated by laser shock waves. This phenomenon is expected to offer a new perspective on the synthesis of complex organic molecules, particularly in relation to the origins of life in space and on Earth.