脑静脉血栓形成的放射临床及危险因素研究:对索马里摩加迪沙某三级医院患者的回顾性分析

IF 2.3 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL International Journal of General Medicine Pub Date : 2025-01-23 eCollection Date: 2025-01-01 DOI:10.2147/IJGM.S485129
Bakar Ali Adam, Ahmed Adam Osman, Mohamed Sheikh Hassan, Nor Osman Sidow, Mohamed Farah Osman Hidig, Abdulkadir Ahmed Mohamed, Abdiwahid Ahmed Ibrahim, Said Abdi Mohamed, Yahye Garad Mohamed, Said Abdirahman Ahmed, Mohamed Osman Omar Jeele, Mohamed Omar Hassan
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引用次数: 0

摘要

背景:脑静脉血栓形成(CVT)是一种罕见但可能危及生命的疾病,其特征是在硬脑膜静脉窦或脑静脉形成血块。CVT表现出多种临床症状,使其诊断具有挑战性。了解与CVT相关的区域差异和具体风险因素至关重要,特别是在索马里等资源匮乏的环境中,流行病学数据有限,卫生保健资源匮乏。目的:本研究旨在探讨索马里摩加迪沙索马里-土耳其雷杰普·塔伊普·埃尔多安研究和培训医院(索马里摩加迪沙的一家三级医院)患者CVT的临床和相关危险因素。方法:我们对2019年1月至2023年12月期间诊断为CVT的68例患者进行了回顾性观察研究。数据包括人口统计信息、临床表现、危险因素和解剖血栓位置。采用描述性统计和卡方检验进行分析。结果:患者以女性为主(86.76%),年龄在20 ~ 40岁之间(86.76%)。产后(77.94%)和妊娠是CVT的主要危险因素,经统计学分析,CVT与产后(χ²= 62.96,p < 0.0001)和妊娠(χ²= 5.21,p = 0.022)有较强的相关性。产后CVT与血栓形成部位相关(p = 0.025)。头痛是主要症状(98.53%),其次是精神状态改变(83.82%)、局灶性运动障碍(80.88%)和癫痫发作(70.59%)。上矢状窦是最常见的受累部位(57.35%)。结论:本研究强调了产后时期是索马里CVT的重要危险因素,并强调了临床警惕和早期干预策略的必要性。需要更大规模的多中心研究来验证这些发现。
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Study of Radioclinical and Risk Factors of Cerebral Venous Thrombosis: A Retrospective Analysis of Patients Presenting to a Tertiary Hospital in Mogadishu, Somalia.

Background: Cerebral venous thrombosis (CVT) is a rare but potentially life-threatening condition characterized by the formation of a blood clot in the dural venous sinuses or cerebral veins. CVT presents a diverse array of clinical symptoms, making its diagnosis challenging. Understanding regional variations and specific risk factors associated with CVT is crucial, especially in low-resource settings like Somalia, where epidemiological data is limited and healthcare resources are scarce.

Objective: This study aims to investigate the clinical and risk factors associated with CVT in patients presenting to Mogadishu Somali-Turkey Recep Tayyip Erdogan Research and Training Hospital, a tertiary hospital in Mogadishu, Somalia.

Methods: We conducted a retrospective observational study involving 68 patients diagnosed with CVT between January 2019 and December 2023. Data included demographic information, clinical presentations, risk factors, and anatomical thrombosis locations. Descriptive statistics and chi-square tests were used for analysis.

Results: The majority of patients were female (86.76%) and aged 20-40 years (86.76%). Significant risk factors included the postpartum period (77.94%) and pregnancy, with statistical analysis showing strong associations between CVT and the postpartum period (χ² = 62.96, p < 0.0001) and pregnancy (χ² = 5.21, p = 0.022). Postpartum CVT was linked to thrombosis location (p = 0.025). Headache was the predominant symptom (98.53%), followed by altered mental status (83.82%), focal motor deficits (80.88%), and seizures (70.59%). The superior sagittal sinus was the most commonly involved site (57.35%).

Conclusion: This study emphasizes the postpartum period as a significant risk factor for CVT in Somalia and highlights the need for clinical vigilance and early intervention strategies. Larger, multicenter studies are needed to validate these findings.

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来源期刊
International Journal of General Medicine
International Journal of General Medicine Medicine-General Medicine
自引率
0.00%
发文量
1113
审稿时长
16 weeks
期刊介绍: The International Journal of General Medicine is an international, peer-reviewed, open access journal that focuses on general and internal medicine, pathogenesis, epidemiology, diagnosis, monitoring and treatment protocols. The journal is characterized by the rapid reporting of reviews, original research and clinical studies across all disease areas. A key focus of the journal is the elucidation of disease processes and management protocols resulting in improved outcomes for the patient. Patient perspectives such as satisfaction, quality of life, health literacy and communication and their role in developing new healthcare programs and optimizing clinical outcomes are major areas of interest for the journal. As of 1st April 2019, the International Journal of General Medicine will no longer consider meta-analyses for publication.
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