{"title":"洞察CKDu的负担","authors":"Susan J. Allison","doi":"10.1038/s41581-025-00935-4","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":19059,"journal":{"name":"Nature Reviews Nephrology","volume":"21 3","pages":"155-155"},"PeriodicalIF":46.7000,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Insights into the burden of CKDu\",\"authors\":\"Susan J. Allison\",\"doi\":\"10.1038/s41581-025-00935-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":19059,\"journal\":{\"name\":\"Nature Reviews Nephrology\",\"volume\":\"21 3\",\"pages\":\"155-155\"},\"PeriodicalIF\":46.7000,\"publicationDate\":\"2025-01-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature Reviews Nephrology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.nature.com/articles/s41581-025-00935-4\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Reviews Nephrology","FirstCategoryId":"3","ListUrlMain":"https://www.nature.com/articles/s41581-025-00935-4","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
不明原因慢性肾脏疾病（CKDu）是一种进行性慢性肾脏疾病（CKD），与CKD的常见危险因素无关，主要影响中低收入国家（LMICs）的成年人。来自弱势群体的研究人员估计肾小球滤过率（eGFR）流行病学（DEGREE）研究现在报告了全球CKDu负担的初步见解。Charlotte Rutter及其同事利用人口代表性调查和分析的数据，估计年龄在18-60岁、无已知CKD病因的成年人中，eGFR的年龄标准化患病率为60 ml/min/1.73 m2，作为CKDu负担的估计。研究人员总共收集了来自14个国家43个地区的60,954名参与者的数据，重点是中低收入国家。在男性中，CKDu的标准化患病率估计在印度Uddanam的农村地区最高(高达13.7%；95% CI 4.8-22.6%)和尼加拉瓜西北部(高达13.6%；95% ci 6.3-20.9%)。男性的高患病率（5%）主要仅在农村地区观察到，但尼加拉瓜莱昂的一个城市地区除外。在妇女中，仅在厄瓜多尔的米格里略（Miguelillo）观察到高患病率(6.0%；95% CI 2.2-9.7%)和Uddanam(高达8%；95% ci 2.0-14.1%)。除中美洲和南亚外，患病率较低（2%）。
期刊介绍：
Nature Reviews Nephrology aims to be the premier source of reviews and commentaries for the scientific communities it serves.
It strives to publish authoritative, accessible articles.
Articles are enhanced with clearly understandable figures, tables, and other display items.
Nature Reviews Nephrology publishes Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements.
The content is relevant to nephrologists and basic science researchers.
The broad scope of the journal ensures that the work reaches the widest possible audience.
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