i2催化nh -亚砜亚胺与二芳基甲烷和烷基烯的苄基化反应。

IF 2.8 3区化学 Q1 CHEMISTRY, ORGANIC Organic & Biomolecular Chemistry Pub Date : 2025-01-16 DOI:10.1039/d4ob01709a

Yiyi Chen , Qisheng Chen , Shuangquan Zhang , Kun Feng , Xianqiang Kong , Xiaohui Chen , Wenjuan Li , Zhong-Yan Cao

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引用次数: 0

摘要

以单质碘为催化剂，过氧化叔丁基（TBHP）为末端氧化剂，提出了一种无过渡金属选择性苯基化nh -亚砜胺的方法。与已知的n -苄基化亚砜亚胺的构建方法相比，我们的方法对二芳基甲烷和烷基芳烃的底物范围都很广，并且可以在空气中进行，具有良好的官能团耐受性。

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I2-Catalyzed benzylation of NH-sulfoximines with diarylmethanes and alkylarenes†

A practical transition metal-free approach for the selective benzylation of NH-sulfoximines has been disclosed by using simple elemental iodine as the catalyst and tert-butyl hydroperoxide (TBHP) as the terminal oxidant. Comparing with known methods for the construction of N-benzylated sulfoximines, our protocol shows broad substrate scope with respect to both diarylmethanes and alkylarenes, and can be conducted in air with good functional group tolerance.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.