磁电纳米颗粒治疗应用的基础见解。

IF 6.4 2区 材料科学 Q1 CHEMISTRY, PHYSICAL Nanoscale Horizons Pub Date : 2025-01-23 DOI:10.1039/D4NH00560K
Victoria Andre, Mostafa Abdel-Mottaleb, Max Shotbolt, Shawnus Chen, Zeinab Ramezini, Elric Zhang, Skye Conlan, Ozzie Telisman, Ping Liang, John M. Bryant, Roman Chomko and Sakhrat Khizroev
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引用次数: 0

摘要

本文回顾了磁电纳米颗粒(MENPs)在生物医学上的应用,提出了基本的物理考虑,以帮助理解未来治疗应用的可能性。目前新兴的应用包括无线非手术神经调节和记录、脑功能测绘、靶向癌症治疗的高特异性细胞电穿孔、靶向药物输送、早期筛查和诊断等。使用从头算分析,从其基本限制的角度讨论每个应用。此外,该综述指出了最突出的挑战,并提供了潜在的工程解决方案,以实现每种应用,并结合纳米颗粒的治疗和诊断能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Foundational insights for theranostic applications of magnetoelectric nanoparticles

Reviewing emerging biomedical applications of MagnetoElectric NanoParticles (MENPs), this paper presents basic physics considerations to help understand the possibility of future theranostic applications. Currently emerging applications include wireless non-surgical neural modulation and recording, functional brain mapping, high-specificity cell electroporation for targeted cancer therapies, targeted drug delivery, early screening and diagnostics, and others. Using an ab initio analysis, each application is discussed from the perspective of its fundamental limitations. Furthermore, the review identifies the most eminent challenges and offers potential engineering solutions on the pathway to implement each application and combine the therapeutic and diagnostic capabilities of the nanoparticles.

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来源期刊
Nanoscale Horizons
Nanoscale Horizons Materials Science-General Materials Science
CiteScore
16.30
自引率
1.00%
发文量
141
期刊介绍: Nanoscale Horizons stands out as a premier journal for publishing exceptionally high-quality and innovative nanoscience and nanotechnology. The emphasis lies on original research that introduces a new concept or a novel perspective (a conceptual advance), prioritizing this over reporting technological improvements. Nevertheless, outstanding articles showcasing truly groundbreaking developments, including record-breaking performance, may also find a place in the journal. Published work must be of substantial general interest to our broad and diverse readership across the nanoscience and nanotechnology community.
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