人造肌肉移植用于治疗体积性肌肉损失的脂肪生成-肌生成信号（Adv. Biology 12/2024）

IF 2.6 3区生物学 Q3 MATERIALS SCIENCE, BIOMATERIALS Advanced biology Pub Date : 2024-12-13 DOI:10.1002/adbi.202470121

Dallas E. Altamirano, Eszter Mihaly, Jalissa D. Emmens, Warren L. Grayson

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摘要

组织工程肌肉移植找到平衡：在电纺丝纤维蛋白微纤维束上生长的人类肌源性祖细胞刺激了体积肌肉损失后的骨骼肌再生。fap样ASCs的递送需要优化，以增加肌肉再生，同时最大限度地减少体内脂肪组织的生长。更多细节可以在Warren L. Grayson及其同事的2400113号文章中找到。

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Adipogenic-Myogenic Signaling in Engineered Human Muscle Grafts used to Treat Volumetric Muscle Loss (Adv. Biology 12/2024)

Tissue Engineered Muscle Grafts

Finding balance: Human myogenic progenitors grown on electrospun fibrin microfiber bundles stimulated skeletal muscle regeneration following volumetric muscle loss. The delivery of FAP-like ASCs requires optimization to increase muscle regeneration while minimizing the adipose tissue growth in vivo. More details can be found in article number 2400113 by Warren L. Grayson and co-workers.

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