{"title":"Gold-Catalyzed Highly Regioselective Hydration of Alkynylsulfonamides for Atom-Economic Synthesis of N-Ketosulfonamides","authors":"Yuguang Wang, Menghao Ma, Yunlong Deng, Panpan Yao, Agui Xing, Wenjing Li, Yuan Chen, Ji'an Wu","doi":"10.1002/aoc.70003","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Gold(I)-catalyzed highly regioselective hydration of alkynylsulfonamides for synthesis of N-ketosulfonamides in 85%–96% yields. The reaction used water as a nucleophile, which had the advantages of mild reaction conditions, good functional group tolerance, high regioselectivity, high yield, and 100% atomic economy (without generating by-products or waste). This might endow this method with great potential in green synthesis of N-ketosulfonamides compounds.</p>\n </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 2","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Organometallic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/aoc.70003","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
Gold-Catalyzed Highly Regioselective Hydration of Alkynylsulfonamides for Atom-Economic Synthesis of N-Ketosulfonamides
Gold(I)-catalyzed highly regioselective hydration of alkynylsulfonamides for synthesis of N-ketosulfonamides in 85%–96% yields. The reaction used water as a nucleophile, which had the advantages of mild reaction conditions, good functional group tolerance, high regioselectivity, high yield, and 100% atomic economy (without generating by-products or waste). This might endow this method with great potential in green synthesis of N-ketosulfonamides compounds.
期刊介绍:
All new compounds should be satisfactorily identified and proof of their structure given according to generally accepted standards. Structural reports, such as papers exclusively dealing with synthesis and characterization, analytical techniques, or X-ray diffraction studies of metal-organic or organometallic compounds will not be considered. The editors reserve the right to refuse without peer review any manuscript that does not comply with the aims and scope of the journal. Applied Organometallic Chemistry publishes Full Papers, Reviews, Mini Reviews and Communications of scientific research in all areas of organometallic and metal-organic chemistry involving main group metals, transition metals, lanthanides and actinides. All contributions should contain an explicit application of novel compounds, for instance in materials science, nano science, catalysis, chemical vapour deposition, metal-mediated organic synthesis, polymers, bio-organometallics, metallo-therapy, metallo-diagnostics and medicine. Reviews of books covering aspects of the fields of focus are also published.