COVID-19大流行期间儿童2型糖尿病发病率的上升以及该病毒作为潜在的致病因素

IF 1.4 Q4 ENDOCRINOLOGY & METABOLISM Diabetes epidemiology and management Pub Date : 2025-04-01 Epub Date: 2025-01-24 DOI:10.1016/j.deman.2025.100258
Andrew Kanouse , Joanna S. Fishbein , Parissa Salemi
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引用次数: 0

摘要

多种人口统计数据显示,2型糖尿病的患病率持续上升,但在2019冠状病毒病大流行期间,发病率增幅尤其大。如COVID-19所示,先前的2型糖尿病诊断通常与病毒感染的更多困难相关,但2型糖尿病的发展与COVID-19病毒感染之间是否存在反向因果关系尚不清楚。我们的目的是确定COVID-19病毒与儿童2型糖尿病的新诊断之间是否存在关联。方法我们在小儿内分泌科的实践中检查了130例新诊断为2型糖尿病的患者,这些患者在大流行出现之前和之后不久被诊断为2型糖尿病,以确定这两个时期之间的表现特征是否有变化。结果我们的数据显示2型糖尿病的发病率增加(p <;0.0001)和较低的平均呈现年龄(p = 0.03),在COVID-19大流行期间,其他参数无差异。结论我们认为,这些结果表明,COVID-19感染后2型糖尿病的发展是由于病毒本身固有的机制,特别是年轻患者的风险增加。
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The rise in incidence of pediatric type 2 diabetes during the COVID-19 pandemic and the virus as a potential causative factor

Aim

The prevalence of type 2 diabetes continues to rise across multiple demographics but there was an especially large increase in incidence during the COVID-19 pandemic. A pre-existing diagnosis of type 2 diabetes is generally associated with more difficulties with viral infections, as seen with COVID-19, but it is less clear if a reverse causal association exists between the development of type 2 diabetes and infection with the COVID-19 virus. Our aim was to determine if an association exists between the COVID-19 virus and new diagnoses of pediatric type 2 diabetes.

Methods

We examined 130 new patients in our pediatric endocrinology practice diagnosed with type 2 diabetes immediately before and just after the emergence of the pandemic to determine if there was a change in presenting characteristics between these two periods.

Results

Our data showed an increase in the incidence of type 2 diabetes (p < 0.0001) and a lower mean presenting age (p = 0.03) during the COVID-19 pandemic without differences in other parameters.

Conclusion

We believe these results suggest that the development of type 2 diabetes following COVID-19 infection is due to mechanisms inherent to the virus itself and that younger patients are especially at an increased risk.
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来源期刊
Diabetes epidemiology and management
Diabetes epidemiology and management Endocrinology, Diabetes and Metabolism, Public Health and Health Policy
CiteScore
1.10
自引率
0.00%
发文量
0
审稿时长
14 days
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