肺指双胞胎

Q4 Medicine Open Respiratory Archives Pub Date : 2024-10-01 Epub Date: 2024-12-12 DOI:10.1016/j.opresp.2024.100394
Ana Fernández-Tena , Carlos Arnedo , Guillaume Houzeaux , Beatriz Eguzkitza
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引用次数: 0

摘要

肺数字双胞胎(DTs)的发展代表了个性化医疗的重大进步,提供了一个虚拟框架,以个性化的方式复制呼吸系统的结构、功能和病理。DTs集成了临床数据、高分辨率图像和数学模型,实时模拟呼吸力学、气体扩散和流体动力学。这项技术改善了诊断、治疗计划和疾病进展监测。肺DTs的关键应用之一是能够模拟患者对治疗的特异性反应并预测结果,从而实现个性化治疗。尽管取得了进步,但在临床实践中实施DTs面临着与数据集成、计算效率和有关数据隐私的伦理考虑相关的挑战。尽管如此,肺部DTs为改善精准医疗、优化患者护理和改善临床结果提供了明确的希望。
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Gemelos digitales pulmonares
The development of lung digital twins (DTs) represents a significant advance in personalized medicine, providing a virtual framework that replicates the structure, function, and pathology of the respiratory system in an individualized manner. DTs integrate clinical data, high-resolution images, and mathematical models to simulate respiratory mechanics, gas diffusion, and fluid dynamics in real time. This technology improves diagnosis, treatment planning, and disease progression monitoring. One of the key applications of lung DTs is the ability to simulate patient-specific response to treatments and predict outcomes, allowing for personalized therapies. Despite advances, the implementation of DTs in clinical practice faces challenges related to data integration, computational efficiency, and ethical considerations regarding data privacy. Nevertheless, lung DTs offer clear promise for improving precision medicine, optimizing patient care, and improving clinical outcomes.
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来源期刊
Open Respiratory Archives
Open Respiratory Archives Medicine-Pulmonary and Respiratory Medicine
CiteScore
1.10
自引率
0.00%
发文量
58
审稿时长
51 days
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