基于证据的鼻窦肿瘤累及眼眶:保留还是切除?IHNSG指南。

IF 4 3区 医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL Advances in Therapy Pub Date : 2025-02-06 DOI:10.1007/s12325-025-03113-x
Karthik N. Rao, Cesare Piazza, Carl Snyderman, Vincent Vander Poorten, M. P. Sreeram, Primož Strojan, Ehab Hanna, Orlando Guntinas-Lichius, Fernando Lopez, Lauge Hjorth Mikkelsen, Carlos Suárez, Akihiro Homma, Silvia Babighian, Luiz P. Kowalski, Alfio Ferlito
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引用次数: 0

摘要

由于眶和窦鼻复调复杂的解剖结构以及潜在的严重肿瘤和治疗相关的发病率,累及眶的鼻窦肿瘤提出了重大的管理挑战。这篇全面的综述探讨了在治疗涉及眼眶的鼻窦恶性肿瘤的背景下基于证据的决策指南。我们评估了治疗前的评估策略,讨论了眼眶保留与眼眶切除的适应症,探讨了新辅助治疗的作用,并分析了重建技术与随后的康复方法和生活质量。我们的综述强调了以患者为中心的多学科治疗方法的必要性,该方法可以优化晚期鼻窦恶性肿瘤伴眼眶受累患者的治疗结果和生活质量。
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Evidence Based Recommendations in Sinonasal Tumors Involving Orbit: Preservation or Exenteration? An IHNSG Guidelines

Sinonasal tumors with orbital involvement present significant management challenges due to the complex anatomy of the orbital and sinonasal complex and the potential for severe tumor- and treatment-related morbidities. This comprehensive review examines evidence-based decision-making guidelines in the context of treating sinonasal malignancies involving the orbit. We evaluate pre-treatment assessment strategies, discuss the indications for orbital preservation versus its exenteration, explore the role of neo-adjuvant therapies, and analyze reconstruction techniques with ensuing rehabilitation approaches and quality of life. Our review underscores the need for a patient-centered multidisciplinary approach that optimizes treatment outcomes and quality of life for patients suffering from such advanced sinonasal malignancies with orbital involvement.

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来源期刊
Advances in Therapy
Advances in Therapy 医学-药学
CiteScore
7.20
自引率
2.60%
发文量
353
审稿时长
6-12 weeks
期刊介绍: Advances in Therapy is an international, peer reviewed, rapid-publication (peer review in 2 weeks, published 3–4 weeks from acceptance) journal dedicated to the publication of high-quality clinical (all phases), observational, real-world, and health outcomes research around the discovery, development, and use of therapeutics and interventions (including devices) across all therapeutic areas. Studies relating to diagnostics and diagnosis, pharmacoeconomics, public health, epidemiology, quality of life, and patient care, management, and education are also encouraged. The journal is of interest to a broad audience of healthcare professionals and publishes original research, reviews, communications and letters. The journal is read by a global audience and receives submissions from all over the world. Advances in Therapy will consider all scientifically sound research be it positive, confirmatory or negative data. Submissions are welcomed whether they relate to an international and/or a country-specific audience, something that is crucially important when researchers are trying to target more specific patient populations. This inclusive approach allows the journal to assist in the dissemination of all scientifically and ethically sound research.
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