选择性激光小梁成形术治疗原发性开角型青光眼粘管造口术后眼压升高:一项回顾性队列研究。

IF 1.7 4区 医学 Q3 OPHTHALMOLOGY BMC Ophthalmology Pub Date : 2025-02-05 DOI:10.1186/s12886-025-03888-1
Ahmed Am Gad, Bahaa-Eldin Hasan Abdulhalim, Amal F Gharib, Amr Mahfouz Mohammed
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摘要

背景:选择性激光小梁成形术(SLT)是青光眼的一种非侵入性治疗选择。它使用调q Nd: YAG激光器。本研究的目的是评估SLT作为原发性开角型青光眼(POAG)的治疗选择的有效性,这些患者之前已经用Ologen植入物进行了粘管造口术,显示眼压(IOP)不受控制。方法:回顾性队列研究包括26例POAG患者的26只眼,这些患者在使用Ologen种植体进行粘管造瘘或超声粘管造瘘后进行了SLT。这些眼睛表现出青光眼损害的进展,IOP高于21 mmHg,或患有无法忍受的青光眼药物。SLT使用Tango Reflex多模态YAG/SLT激光器完成,该激光器是一种调q Nd: YAG激光器,产生单个532 nm波长脉冲,光斑尺寸为400 mm,脉冲持续时间为3ns。随访期为一年。结果:slt术后1年,完全成功19例(73.1%),合格成功4例(15.4%),不成功3例(11.5%)。眼压平均下降5.64±4.05 mmHg,抗青光眼药物平均下降1.00±0.85,眼压平均下降百分比为23.5±16.4%。结论:SLT是一种简单有效的治疗方法,可作为POAG患者在使用Ologen种植体进行粘管吻合术后达到目标IOP和减少抗青光眼药物用量的治疗选择。
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Selective laser trabeculoplasty for the treatment of intraocular pressure elevation after viscocanalostomy with Ologen implant in the management of primary open-angle glaucoma: a retrospective cohort study.

Background: Selective laser trabeculoplasty (SLT) is a non-invasive treatment option for glaucoma. It uses a Q-switched Nd: YAG laser. The aim of this study was to evaluate the efficacy of SLT as a treatment option for eyes with primary open-angle glaucoma (POAG) that have previously undergone viscocanalostomy with an Ologen implant, displaying uncontrolled intraocular pressure (IOP).

Methods: This retrospective cohort study included 26 eyes of 26 patients with POAG who had had SLT after viscocanalostomy or phacoviscocanalostomy with Ologen implant. These eyes showed a progression of glaucomatous damage, the IOP was above 21 mmHg, or with intolerable glaucoma medications. SLT was done using Tango Reflex multimodality YAG/SLT laser which is a Q-switched Nd: YAG laser producing a single 532 nm wavelength pulse with a 400 mm spot size and 3 ns pulse duration. The follow-up period was one year.

Results: One year post-SLT, complete success was achieved in 19 cases (73.1%), qualified success in 4 cases (15.4%), and failure in 3 cases (11.5%). The mean decrease in IOP was 5.64 ± 4.05 mmHg, the mean reduction of antiglaucoma medications was 1.00 ± 0.85, and the mean percentage of reduction in IOP was 23.5 ± 16.4. There was a statistically significant decrease in IOP and antiglaucoma medications (p = < 0.01).

Conclusion: SLT is a simple and effective procedure that can be used as a treatment option for eyes with POAG after viscocanalostomy with Ologen implant to reach the target IOP and decrease the number of antiglaucoma medications.

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来源期刊
BMC Ophthalmology
BMC Ophthalmology OPHTHALMOLOGY-
CiteScore
3.40
自引率
5.00%
发文量
441
审稿时长
6-12 weeks
期刊介绍: BMC Ophthalmology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of eye disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
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