一种新的数据压缩无损编码算法——以基因组数据为例。

IF 3.9 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Frontiers in bioinformatics Pub Date : 2025-01-23 eCollection Date: 2024-01-01 DOI:10.3389/fbinf.2024.1489704
Anas Al-Okaily, Abdelghani Tbakhi
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引用次数: 0

摘要

数据压缩是一个具有挑战性和日益重要的问题。随着每天产生的数据量不断增加,高效的传输和存储变得前所未有的重要。在这项研究中,提出了一种新的编码算法,以压缩DNA数据和相关特征为动机。该算法采用分而治之的方法,通过扫描整个基因组,根据其内容的相似性对子序列进行分类,并将相似的子序列合并在一起。然后将数据独立地压缩到每个bin中。这种方法不同于目前已知的方法:熵、字典、预测或基于转换的方法。概念验证性能使用一个基准数据集进行评估,该数据集包含17个基因组,大小从千字节到千兆字节不等。结果显示,与最先进的工具相比,每个基因组的压缩有了相当大的改进,保留了几兆字节。此外,该算法还可以应用于其他数据类型的压缩,主要包括文本、数字、图像、音频和视频,这些数据类型每天都在产生,并且数量空前庞大。
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A novel lossless encoding algorithm for data compression-genomics data as an exemplar.

Data compression is a challenging and increasingly important problem. As the amount of data generated daily continues to increase, efficient transmission and storage have never been more critical. In this study, a novel encoding algorithm is proposed, motivated by the compression of DNA data and associated characteristics. The proposed algorithm follows a divide-and-conquer approach by scanning the whole genome, classifying subsequences based on similarities in their content, and binning similar subsequences together. The data is then compressed into each bin independently. This approach is different than the currently known approaches: entropy, dictionary, predictive, or transform-based methods. Proof-of-concept performance was evaluated using a benchmark dataset with seventeen genomes ranging in size from kilobytes to gigabytes. The results showed a considerable improvement in the compression of each genome, preserving several megabytes compared to state-of-the-art tools. Moreover, the algorithm can be applied to the compression of other data types include mainly text, numbers, images, audio, and video which are being generated daily and unprecedentedly in massive volumes.

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