Matthew R Golden, Ryan T Taketomo, Ryan Pistoresi, Donna Sullivan
{"title":"取消华盛顿州医疗补助计划对抗逆转录病毒药物的优先授权对预算的影响。","authors":"Matthew R Golden, Ryan T Taketomo, Ryan Pistoresi, Donna Sullivan","doi":"10.1097/OLQ.0000000000002136","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>In 2023, Washington state Medicaid eliminated prior authorizations (PAs) for antiretrovirals (ARVs). We estimated the budget impact of this policy change on Medicaid ARV expenditures, 2023 to 2027.</p><p><strong>Methods: </strong>Models used 2022 net drug costs reflecting costs minus rebates. Our base case preexposure prophylaxis (PrEP) model assumed changes in the proportions of PrEP users on tenofovir disoproxil fumarate/emtricitabine (TDF/FTC), tenofovir alafenamide/emtricitabine (TAF/FTC), and cabotegravir (CAB) based on 2021-2022 data (before elimination of PAs). We compared base case costs to models assuming changes in PrEP prescribing observed in 2022 to 2023 (first year after elimination of PAs) and models assuming an accelerated increase in TAF/FTC and CAB use. For HIV treatment, models assuming ARV changes based on 2021 to 2022 data (Base Model), changes based on data from 2022 to 2023 (No PA-Stable Increase), and a model based on 2022 to 2023 data but with a declining rate of change in the adoption of bictegravir/TAF/FTC and CAB/rilpivirine (No PA-Declining Increase). We estimated the number of persons with HIV who might be housed using money required to meet new ARV costs using 2023 local Ryan White Program costs for emergency or temporary housing.</p><p><strong>Results: </strong>Elimination of PAs will increase Medicaid expenditures for ARVs by an estimated $109.9 to $157.7 million over 5 years. This cost would pay for 5 years of housing for approximately 820 to 1177 people, or 61% to 88% of unstably housed persons with HIV in Washington state.</p><p><strong>Conclusions: </strong>Elimination of Medicaid PAs will result in substantial new costs. Changes in drug formulary policy should consider opportunity costs.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"370-375"},"PeriodicalIF":1.7000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Budget Impact of Eliminating Medicaid Prior Authorizations for Antiretrovirals in Washington State.\",\"authors\":\"Matthew R Golden, Ryan T Taketomo, Ryan Pistoresi, Donna Sullivan\",\"doi\":\"10.1097/OLQ.0000000000002136\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>In 2023, Washington state Medicaid eliminated prior authorizations (PAs) for antiretrovirals (ARVs). We estimated the budget impact of this policy change on Medicaid ARV expenditures, 2023 to 2027.</p><p><strong>Methods: </strong>Models used 2022 net drug costs reflecting costs minus rebates. Our base case preexposure prophylaxis (PrEP) model assumed changes in the proportions of PrEP users on tenofovir disoproxil fumarate/emtricitabine (TDF/FTC), tenofovir alafenamide/emtricitabine (TAF/FTC), and cabotegravir (CAB) based on 2021-2022 data (before elimination of PAs). We compared base case costs to models assuming changes in PrEP prescribing observed in 2022 to 2023 (first year after elimination of PAs) and models assuming an accelerated increase in TAF/FTC and CAB use. For HIV treatment, models assuming ARV changes based on 2021 to 2022 data (Base Model), changes based on data from 2022 to 2023 (No PA-Stable Increase), and a model based on 2022 to 2023 data but with a declining rate of change in the adoption of bictegravir/TAF/FTC and CAB/rilpivirine (No PA-Declining Increase). 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引用次数: 0
摘要
背景:2023年,华盛顿州医疗补助计划取消了抗逆转录病毒药物(ARVs)的事先授权(PAs)。我们估计了2023-2027年这一政策变化对医疗补助ARV支出的预算影响。方法:模型采用2022年净药品成本,反映成本减去回扣。我们的基本病例暴露前预防(PrEP)模型基于2021-2022年的数据(在消除PAs之前),假设PrEP使用者使用富马酸替诺福韦二氧吡酯/恩曲他滨(TDF/FTC)、替诺福韦阿拉胺/恩曲他滨(TAF/FTC)和卡波特韦(CAB)的比例发生变化。我们将基本情况成本与假设2022-2023年(取消PAs后的第一年)PrEP处方发生变化的模型和假设TAF/FTC和CAB使用加速增加的模型进行了比较。对于艾滋病毒治疗,模型假设基于2021-2022年数据的ARV变化(基础模型),基于2022-2023年数据的变化(无PA -稳定增长),以及基于2022-2023年数据的模型,但采用比替格雷韦/TAF/FTC和CAB/里尔匹韦林的变变率下降(无PA -下降增长)。我们估计了艾滋病病毒感染者(PWH)的数量,他们可能会使用2023年当地瑞恩·怀特计划(Ryan White Program)的紧急或临时住房费用来支付新的抗逆转录病毒治疗费用。结果:取消PAs将在5年内增加用于抗逆转录病毒药物的医疗补助支出,估计为1.099亿至1.577亿美元。这笔费用将为大约820- 1177人支付5年的住房费用,占华盛顿州住房不稳定的PWH的61-88%。结论:取消医疗补助PAs将导致大量的新成本。改变药物处方政策应考虑机会成本。
Budget Impact of Eliminating Medicaid Prior Authorizations for Antiretrovirals in Washington State.
Background: In 2023, Washington state Medicaid eliminated prior authorizations (PAs) for antiretrovirals (ARVs). We estimated the budget impact of this policy change on Medicaid ARV expenditures, 2023 to 2027.
Methods: Models used 2022 net drug costs reflecting costs minus rebates. Our base case preexposure prophylaxis (PrEP) model assumed changes in the proportions of PrEP users on tenofovir disoproxil fumarate/emtricitabine (TDF/FTC), tenofovir alafenamide/emtricitabine (TAF/FTC), and cabotegravir (CAB) based on 2021-2022 data (before elimination of PAs). We compared base case costs to models assuming changes in PrEP prescribing observed in 2022 to 2023 (first year after elimination of PAs) and models assuming an accelerated increase in TAF/FTC and CAB use. For HIV treatment, models assuming ARV changes based on 2021 to 2022 data (Base Model), changes based on data from 2022 to 2023 (No PA-Stable Increase), and a model based on 2022 to 2023 data but with a declining rate of change in the adoption of bictegravir/TAF/FTC and CAB/rilpivirine (No PA-Declining Increase). We estimated the number of persons with HIV who might be housed using money required to meet new ARV costs using 2023 local Ryan White Program costs for emergency or temporary housing.
Results: Elimination of PAs will increase Medicaid expenditures for ARVs by an estimated $109.9 to $157.7 million over 5 years. This cost would pay for 5 years of housing for approximately 820 to 1177 people, or 61% to 88% of unstably housed persons with HIV in Washington state.
Conclusions: Elimination of Medicaid PAs will result in substantial new costs. Changes in drug formulary policy should consider opportunity costs.
期刊介绍:
Sexually Transmitted Diseases, the official journal of the American Sexually Transmitted Diseases Association, publishes peer-reviewed, original articles on clinical, laboratory, immunologic, epidemiologic, behavioral, public health, and historical topics pertaining to sexually transmitted diseases and related fields. Reports from the CDC and NIH provide up-to-the-minute information. A highly respected editorial board is composed of prominent scientists who are leaders in this rapidly changing field. Included in each issue are studies and developments from around the world.