{"title":"优化光子计数CT肠造影：确定肠成像的最佳虚拟单能量。","authors":"Arghavan Sharifi, Thomas O’Donnell, Bari Dane","doi":"10.1007/s00261-025-04832-z","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>To determine the optimal virtual monoenergy for viewing the bowel at photon-counting CT enterography using quantitative assessment of mural attenuation, contrast-to-noise ratio, signal-to-noise ratio and noise.</p><h3>Methods</h3><p>This study was institutional review board approved and Health Insurance Portability and Accountability Act compliant. Consecutive adults (≥ 18 years) who underwent photon-counting CT enterography from 5/1/2022-5/31/2022 with available Spectral Postprocessing (SPP) images for retrospective virtual monoenergy creation were identified. Nine virtual monoenergetic series (40–120 keV, 10 keV increments) were created. Two region–of-interest measurements were placed in the stomach wall, jejunum wall, ileum wall, and each psoas muscle by two radiologists on 0.6 mm images in PACS. Region-of-interests were copied to other virtual monoenergies to ensure identical placement and size. Attenuation (HU) and noise (HU standard deviation) were recorded from each region-of-interest. Signal-to-noise ratio and contrast-to-noise ratio were computed for stomach, jejunum, ileum, and all bowel combined. Pairwise comparisons for attenuation, noise, signal-to-noise ratio and contrast-to-noise ratio for each virtual monoenergy were performed with ANOVA. A <i>p</i> <.05 indicated statistical significance.</p><h3>Results</h3><p>50 patients (32 female; mean[SD] age: 57 years) were included. Attenuation and noise for all bowel regions were highest at 40 keV with statistically significant pairwise comparisons from 40 to 70 keV (all <i>p</i> <.05), but similar for 70-120 keV (all <i>p</i> >.05). Signal-to-noise ratio was similar from 40 to 70 keV (all <i>p</i> >.05) for all bowel regions. Contrast-to-noise ratio decreased with increasing keV. Contrast-to-noise ratio was similar for all bowel at 40 keV and 50 keV (<i>p</i> =.06), for stomach from 40 to 70 keV (all <i>p</i> >.05), for jejunum from 40 to 50 keV (<i>p</i> =.21), and for ileum from 40 to 60 keV (all <i>p</i> >.05).</p><h3>Conclusion</h3><p>50 keV virtual monoenergetic images from photon-counting CT enterography optimizes contrast-to-noise ratio while mitigating noise and should routinely be utilized for bowel assessment at photon-counting CT enterography. As most photon-counting CT users primarily interpret virtual monoenergetic images in clinical practice, knowledge of the optimal virtual monoenergy can inform protocol development.</p></div>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":"50 9","pages":"3928 - 3935"},"PeriodicalIF":2.3000,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Optimizing photon counting CT enterography: determining the optimal virtual monoenergy for bowel imaging\",\"authors\":\"Arghavan Sharifi, Thomas O’Donnell, Bari Dane\",\"doi\":\"10.1007/s00261-025-04832-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>To determine the optimal virtual monoenergy for viewing the bowel at photon-counting CT enterography using quantitative assessment of mural attenuation, contrast-to-noise ratio, signal-to-noise ratio and noise.</p><h3>Methods</h3><p>This study was institutional review board approved and Health Insurance Portability and Accountability Act compliant. Consecutive adults (≥ 18 years) who underwent photon-counting CT enterography from 5/1/2022-5/31/2022 with available Spectral Postprocessing (SPP) images for retrospective virtual monoenergy creation were identified. Nine virtual monoenergetic series (40–120 keV, 10 keV increments) were created. Two region–of-interest measurements were placed in the stomach wall, jejunum wall, ileum wall, and each psoas muscle by two radiologists on 0.6 mm images in PACS. Region-of-interests were copied to other virtual monoenergies to ensure identical placement and size. Attenuation (HU) and noise (HU standard deviation) were recorded from each region-of-interest. Signal-to-noise ratio and contrast-to-noise ratio were computed for stomach, jejunum, ileum, and all bowel combined. Pairwise comparisons for attenuation, noise, signal-to-noise ratio and contrast-to-noise ratio for each virtual monoenergy were performed with ANOVA. A <i>p</i> <.05 indicated statistical significance.</p><h3>Results</h3><p>50 patients (32 female; mean[SD] age: 57 years) were included. Attenuation and noise for all bowel regions were highest at 40 keV with statistically significant pairwise comparisons from 40 to 70 keV (all <i>p</i> <.05), but similar for 70-120 keV (all <i>p</i> >.05). Signal-to-noise ratio was similar from 40 to 70 keV (all <i>p</i> >.05) for all bowel regions. Contrast-to-noise ratio decreased with increasing keV. Contrast-to-noise ratio was similar for all bowel at 40 keV and 50 keV (<i>p</i> =.06), for stomach from 40 to 70 keV (all <i>p</i> >.05), for jejunum from 40 to 50 keV (<i>p</i> =.21), and for ileum from 40 to 60 keV (all <i>p</i> >.05).</p><h3>Conclusion</h3><p>50 keV virtual monoenergetic images from photon-counting CT enterography optimizes contrast-to-noise ratio while mitigating noise and should routinely be utilized for bowel assessment at photon-counting CT enterography. As most photon-counting CT users primarily interpret virtual monoenergetic images in clinical practice, knowledge of the optimal virtual monoenergy can inform protocol development.</p></div>\",\"PeriodicalId\":7126,\"journal\":{\"name\":\"Abdominal Radiology\",\"volume\":\"50 9\",\"pages\":\"3928 - 3935\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2025-02-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Abdominal Radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00261-025-04832-z\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Abdominal Radiology","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00261-025-04832-z","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Optimizing photon counting CT enterography: determining the optimal virtual monoenergy for bowel imaging
Objective
To determine the optimal virtual monoenergy for viewing the bowel at photon-counting CT enterography using quantitative assessment of mural attenuation, contrast-to-noise ratio, signal-to-noise ratio and noise.
Methods
This study was institutional review board approved and Health Insurance Portability and Accountability Act compliant. Consecutive adults (≥ 18 years) who underwent photon-counting CT enterography from 5/1/2022-5/31/2022 with available Spectral Postprocessing (SPP) images for retrospective virtual monoenergy creation were identified. Nine virtual monoenergetic series (40–120 keV, 10 keV increments) were created. Two region–of-interest measurements were placed in the stomach wall, jejunum wall, ileum wall, and each psoas muscle by two radiologists on 0.6 mm images in PACS. Region-of-interests were copied to other virtual monoenergies to ensure identical placement and size. Attenuation (HU) and noise (HU standard deviation) were recorded from each region-of-interest. Signal-to-noise ratio and contrast-to-noise ratio were computed for stomach, jejunum, ileum, and all bowel combined. Pairwise comparisons for attenuation, noise, signal-to-noise ratio and contrast-to-noise ratio for each virtual monoenergy were performed with ANOVA. A p <.05 indicated statistical significance.
Results
50 patients (32 female; mean[SD] age: 57 years) were included. Attenuation and noise for all bowel regions were highest at 40 keV with statistically significant pairwise comparisons from 40 to 70 keV (all p <.05), but similar for 70-120 keV (all p >.05). Signal-to-noise ratio was similar from 40 to 70 keV (all p >.05) for all bowel regions. Contrast-to-noise ratio decreased with increasing keV. Contrast-to-noise ratio was similar for all bowel at 40 keV and 50 keV (p =.06), for stomach from 40 to 70 keV (all p >.05), for jejunum from 40 to 50 keV (p =.21), and for ileum from 40 to 60 keV (all p >.05).
Conclusion
50 keV virtual monoenergetic images from photon-counting CT enterography optimizes contrast-to-noise ratio while mitigating noise and should routinely be utilized for bowel assessment at photon-counting CT enterography. As most photon-counting CT users primarily interpret virtual monoenergetic images in clinical practice, knowledge of the optimal virtual monoenergy can inform protocol development.
期刊介绍：
Abdominal Radiology seeks to meet the professional needs of the abdominal radiologist by publishing clinically pertinent original, review and practice related articles on the gastrointestinal and genitourinary tracts and abdominal interventional and radiologic procedures. Case reports are generally not accepted unless they are the first report of a new disease or condition, or part of a special solicited section.
Reasons to Publish Your Article in Abdominal Radiology:
· Official journal of the Society of Abdominal Radiology (SAR)
· Published in Cooperation with:
European Society of Gastrointestinal and Abdominal Radiology (ESGAR)
European Society of Urogenital Radiology (ESUR)
Asian Society of Abdominal Radiology (ASAR)
· Efficient handling and Expeditious review
· Author feedback is provided in a mentoring style
· Global readership
· Readers can earn CME credits
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