α-芳基乙烯基和丙炔磺酸盐与亲核碳试剂的级联反应：合成功能化苄基和均烯丙基硫醚。

IF 2.7 3区化学 Q1 CHEMISTRY, ORGANIC Organic & Biomolecular Chemistry Pub Date : 2025-01-28 Epub Date: 2025-02-06 DOI:10.1039/d5ob00087d

Vilas M. Awchar , Sundarababu Baskaran

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引用次数: 0

摘要

我们报道了α-芳基乙烯基和丙基磺盐与c -亲核试剂的级联反应，分别生成了功能化苄基和均烯丙基硫醚，收率很高。在这个新反应中，乙烯基磺酸衍生物与c -亲核试剂进行迈克尔加成，然后进行[2,3]-异位重排。这种多米诺骨牌反应非常普遍，在温和的条件下也很容易发生。

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Cascade reaction of α-aryl vinyl and propargyl sulfonium salts with carbon nucleophiles: synthesis of functionalized benzyl and homoallyl thioethers†

We report a cascade reaction of α-aryl vinyl and propargyl sulfonium salts with C-nucleophiles, resulting in the formation of functionalized benzyl and homoallyl thioethers, respectively, in good yields. In this novel reaction, a vinyl sulfonium derivative undergoes Michael addition with a C-nucleophile followed by [2,3]-sigmatropic rearrangement. This domino reaction is very general and takes place readily under mild conditions.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.