IF 2.8 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES Supportive Care in Cancer Pub Date : 2025-02-13 DOI:10.1007/s00520-025-09160-y
Mari Kitashita
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引用次数: 0

摘要

研究目的本研究旨在阐明接受癌症药物治疗的晚期癌症患者的希望、心理困扰和生活质量(QOL)之间的关系及其相关因素:研究对象为接受门诊药物治疗的晚期肺癌、结直肠癌和乳腺癌患者。在横断面调查中使用赫氏希望指数、医院焦虑抑郁量表和癌症治疗功能评估--一般作为测量工具。数据分析采用了描述性统计、相关分析、t 检验、单因素方差分析和结构方程模型:问卷调查的有效答卷数为 200 份(91.7%)。SEM包括希望、心理困扰、QOL、社会支持、经济贫困、身体症状和工作表现状况。SEM 的拟合优度指数为 0.989,调整后的拟合优度指数为 0.960,比较拟合指数为 1.000,近似均方根误差为 0.001。希望对心理困扰有负面影响(β = - 0.46),对 QOL 有正面影响(β = .19):结论:研究表明,在接受药物治疗的晚期癌症患者中,希望是心理压力和生活质量的预测因素。社会支持和经济贫困是希望的预测因素。研究结果表明,对希望水平较低的患者进行早期干预,可有效减轻患者的焦虑和抑郁情绪,改善其生活质量。
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Structural equation modeling of hope, psychological distress, quality of life, and influencing factors in advanced cancer patients undergoing cancer pharmacotherapy in Japan.

Objective: The purpose of this study was to clarify the relationship between hope, psychological distress, and quality of life (QOL) of patients with advanced cancer undergoing cancer pharmacotherapy and their related factors.

Methods: Participants were patients with advanced lung, colorectal, and breast cancer undergoing outpatient pharmacotherapy. The Herth Hope Index, Hospital Anxiety and Depression Scale, and Functional Assessment of Cancer Therapy-General were used as measurement tools in a cross-sectional survey. Data were analyzed using descriptive statistics, correlation analysis, t-test, one-way analysis of variance (ANOVA), and Structural Equation Modeling (SEM).

Results: The number of valid responses to the questionnaire survey was 200 (91.7%). SEM included hope, psychological distress, QOL, social support, economic deprivation, physical symptoms, and performance status. The goodness of fit index for SEM was 0.989, adjusted goodness of fit index was 0.960, comparative fit index was 1.000, and root mean square error of approximation was 0.001. Hope had a negative impact on psychological distress (β = - 0.46) and a positive impact on QOL (β = .19).

Conclusion: Hope was shown to be a predictor of psychological distress and QOL in patients with advanced cancer receiving pharmacotherapy. Predictors of hope were social support and economic deprivation. The results suggest that early intervention for patients with characteristics that tend to lower levels of hope is effective in reducing patient anxiety and depression and improving QOL.

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来源期刊
Supportive Care in Cancer
Supportive Care in Cancer 医学-康复医学
CiteScore
5.70
自引率
9.70%
发文量
751
审稿时长
3 months
期刊介绍: Supportive Care in Cancer provides members of the Multinational Association of Supportive Care in Cancer (MASCC) and all other interested individuals, groups and institutions with the most recent scientific and social information on all aspects of supportive care in cancer patients. It covers primarily medical, technical and surgical topics concerning supportive therapy and care which may supplement or substitute basic cancer treatment at all stages of the disease. Nursing, rehabilitative, psychosocial and spiritual issues of support are also included.
期刊最新文献
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