术前阿片类药物依赖与全踝关节置换术后成本增加和伤口开裂相关。

IF 2 3区 医学 Q2 ORTHOPEDICS Foot and Ankle Surgery Pub Date : 2025-07-01 Epub Date: 2025-02-07 DOI:10.1016/j.fas.2025.01.012
Weston E. McDonald, Alexander S. Guareschi, Joshua L. Morningstar, Richard J. Friedman, Christopher E. Gross, Daniel J. Scott
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引用次数: 0

摘要

本研究的目的是评估慢性阿片类药物依赖对原发性全踝关节置换术(TAA)术后预后的影响。方法:查询全国再入院数据库(NRD),从2016年到2020年确定29,751例接受初级选择性TAA的患者,并根据术前阿片类药物依赖的存在将患者分为队列(861例;2.9 %)。结果:整个队列以男性为主(54.2 %),平均年龄为64.15岁(17-90岁),Charlson-Deyo合并症指数评分为0.65(0-12)。术前阿片类药物依赖可显著预测伤口裂开的风险增加(OR=5.365;p 结论:术前长期使用阿片类药物可显著预测较高的术后并发症、LOS发生率和TAA住院费用。证据等级:III级,回顾性队列研究。
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Preoperative opioid dependence associated with increased costs and wound dehiscence following total ankle arthroplasty

Introduction

The purpose of this study is to evaluate the influence of chronic opioid dependence on postoperative outcomes following primary total ankle arthroplasty (TAA).

Methods

The Nationwide Readmissions Database (NRD) was queried from 2016 to 2020 to identify 29,751 patients undergoing primary elective TAA with patients divided into cohorts based on the presence of preoperative opioid dependence (861 patients; 2.9 %).

Results

The overall cohort was majority male (54.2 %) with mean age of 64.15 (range 17–90) years, and Charlson-Deyo Comorbidity Index score of 0.65 (range 0–12). Preoperative opioid dependence was significantly predictive of increased risk of wound dehiscence (OR=5.365; p < .001), adverse discharge (OR=1.443; p < .001), extended stay greater than 4 days (OR= 1.438; p < .001), and more than a $1000 increase in the total cost of admission (β= 1052.27; p = .027).

Conclusion

Chronic preoperative opioid use was significantly predictive of higher rates of postoperative complications, LOS, and substantially higher cost of admission for TAA.

Level of evidence

Level III, Retrospective Cohort Study
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来源期刊
Foot and Ankle Surgery
Foot and Ankle Surgery ORTHOPEDICS-
CiteScore
4.60
自引率
16.00%
发文量
202
期刊介绍: Foot and Ankle Surgery is essential reading for everyone interested in the foot and ankle and its disorders. The approach is broad and includes all aspects of the subject from basic science to clinical management. Problems of both children and adults are included, as is trauma and chronic disease. Foot and Ankle Surgery is the official journal of European Foot and Ankle Society. The aims of this journal are to promote the art and science of ankle and foot surgery, to publish peer-reviewed research articles, to provide regular reviews by acknowledged experts on common problems, and to provide a forum for discussion with letters to the Editors. Reviews of books are also published. Papers are invited for possible publication in Foot and Ankle Surgery on the understanding that the material has not been published elsewhere or accepted for publication in another journal and does not infringe prior copyright.
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