Chong Jung Nam, Nur Fatini Ilyana Mohamat Johari, Sulaiman Khan, Siti Maznah Kabeb, Farah Hanani Zulkifli
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引用次数: 0
摘要
本研究旨在分析交联剂对羟乙基纤维素和聚乙烯醇(PVA)与纤维素纳米晶多孔支架共混生物聚合体的影响。羟乙基纤维素/聚乙烯醇(PVA)/纳米纤维素晶体(HEC/PVA/CNC)通过两种不同的聚合物溶液(戊二醛(GA)(1 wt.%)和氯化钙(20 wt.%))进行交联。通过场电子扫描电子显微镜(FESEM)、傅立叶变换红外光谱(FTIR)、热重分析(TGA)、降解和机械性能研究对交联支架的理化性能进行了比较。结果表明,交联过程改善了所制支架的性能,其中 GA 有机化合物的效果更为显著。总之,HEC/PVA/CNC 支架具有良好的理化性能,可作为组织工程应用的潜在基底。
Effect of Crosslinking Agent on the Cellulose Nanocrystals Reinforced Hydroxyethyl Cellulose/Poly(Vinyl Alcohol) Scaffolds
The aim of this study is to analyze the effect of the crosslinking agent on the blend bioplolymerized hydroxyethyl cellulose and poly(vinyl alcohol) (PVA) with cellulose nanocrystal porous scaffolds. The hydroxyethyl cellulose/PVA/crystal nanocellulose (HEC/PVA/CNC) is crosslinked by using two different polymer solutions which are glutaraldehyde (GA) (1 wt.%) and calcium chloride (20 wt.%). The comparison on the physicochemical properties of the crosslinked scaffolds is characterized via field electron scanning electron microscope (FESEM), Fourier transform infrared (FTIR), TGA, degradation, and mechanical properties studies. The results show that the properties of fabricated scaffolds are improved by crosslinking process with more prominent results on GA organic compound. Overall, the HEC/PVA/CNC scaffolds are exhibited good physicochemical properties and can be considered as potential substrate for tissue engineering applications.
期刊介绍:
Macromolecular Symposia presents state-of-the-art research articles in the field of macromolecular chemistry and physics. All submitted contributions are peer-reviewed to ensure a high quality of published manuscripts. Accepted articles will be typeset and published as a hardcover edition together with online publication at Wiley InterScience, thereby guaranteeing an immediate international dissemination.