钯(II)/路易斯酸催化2-苯并氨基吡啶与丙烯酸酯的氧化烯烃反应:合成异吲哚酮。

IF 2.7 3区 化学 Q1 CHEMISTRY, ORGANIC Organic & Biomolecular Chemistry Pub Date : 2025-01-28 Epub Date: 2025-02-10 DOI:10.1039/d5ob00021a
Dharmik M. Patel , Raj N. Patel , Nileshkumar B. Rathod , Sachinkumar D. Patel , Dinesh G. Thakur , Mahesh A. Sonawane , Subhash Chandra Ghosh
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引用次数: 0

摘要

研究了钯(II)/路易斯酸催化2-苯并氨基吡啶- 1-氧化物与丙烯酸酯的碳氢烯化反应,并在分子内进行了aza-Michael加成反应,合成了异吲哚酮。杂双金属钯(II)/铜(II)催化剂的使用提高了反应效率,使合成一种潜在的抗镇静剂成为可能。
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Palladium(ii)/Lewis acid catalyzed oxidative olefination of 2-benzamidopyridine 1-oxide with acrylates: synthesis of isoindolinones†
A palladium(ii)/Lewis acid-catalyzed C–H olefination of 2-benzamidopyridine 1-oxide with acrylates followed by intramolecular aza-Michael addition for the synthesis of isoindolinones has been developed. The use of a heterobimetallic Pd(ii)/Cu(ii) catalyst enhances the efficiency of the reaction, enabling the synthesis of a potential anti-sedative agent.
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来源期刊
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry 化学-有机化学
CiteScore
5.50
自引率
9.40%
发文量
1056
审稿时长
1.3 months
期刊介绍: Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.
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