Dharmik M. Patel , Raj N. Patel , Nileshkumar B. Rathod , Sachinkumar D. Patel , Dinesh G. Thakur , Mahesh A. Sonawane , Subhash Chandra Ghosh
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Palladium(ii)/Lewis acid catalyzed oxidative olefination of 2-benzamidopyridine 1-oxide with acrylates: synthesis of isoindolinones†
A palladium(ii)/Lewis acid-catalyzed C–H olefination of 2-benzamidopyridine 1-oxide with acrylates followed by intramolecular aza-Michael addition for the synthesis of isoindolinones has been developed. The use of a heterobimetallic Pd(ii)/Cu(ii) catalyst enhances the efficiency of the reaction, enabling the synthesis of a potential anti-sedative agent.
期刊介绍:
Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.