以泌尿道结石为首发症状的原发性甲状旁腺功能亢进1例。

IF 0.6 4区 医学 Q4 MEDICAL LABORATORY TECHNOLOGY Clinical laboratory Pub Date : 2025-02-01 DOI:10.7754/Clin.Lab.2024.240838
Gangfeng Li, Qian Wang, Ningping Shan
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引用次数: 0

摘要

背景:原发性甲状旁腺功能亢进(PHPT)是甲状旁腺病变引起甲状旁腺激素(PTH)分泌过多,导致血清钙高、磷低,导致消化道溃疡、尿路结石等症状的疾病。方法:我们报告一例高血钙低血磷的多发性尿路结石。经调查,发现病因是原发性甲状旁腺功能亢进。结果:患者血清甲状旁腺素水平明显升高。同时,颈部超声显示甲状旁腺瘤的存在。因此,认为患者有PHPT导致高血钙、低血磷,导致多发尿路结石。结论:尿路结石患者血钙水平高、血磷水平低时,实验室人员应考虑PHPT的可能性。同时测量甲状旁腺激素水平,及时提醒临床医生对患者进行甲状旁腺超声等检查,减少漏诊的可能性。
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A Case of Primary Hyperparathyroidism with Urinary Tract Stones as the Initial Symptom.

Background: Primary hyperparathyroidism (PHPT) is a disease caused by excessive secretion of parathyroid hormone (PTH) due to parathyroid gland lesions, resulting in high serum calcium and low phosphorus, leading to symptoms such as digestive ulcers and urinary tract stones.

Methods: We report a case of multiple urinary tract stones with high serum calcium and low serum phosphorus. Upon investigation, it was found that the cause was primary hyperparathyroidism.

Results: The serum PTH level of the patient was detected to be significantly elevated. At the same time, neck ultra-sound showed the presence of a parathyroid adenoma. Therefore, it is believed that the patient has PHPT causing high serum calcium and low serum phosphorus, leading to multiple urinary tract stones.

Conclusions: When patients with urinary tract stones have high serum calcium levels and low serum phosphorus levels, laboratory personnel should consider the possibility of PHPT. Simultaneously measuring PTH levels and promptly reminding clinical doctors to perform parathyroid ultrasound and other examinations on patients to reduce the possibility of a missed PHPT diagnosis.

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来源期刊
Clinical laboratory
Clinical laboratory 医学-医学实验技术
CiteScore
1.50
自引率
0.00%
发文量
494
审稿时长
3 months
期刊介绍: Clinical Laboratory is an international fully peer-reviewed journal covering all aspects of laboratory medicine and transfusion medicine. In addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies. The journal publishes original articles, review articles, posters, short reports, case studies and letters to the editor dealing with 1) the scientific background, implementation and diagnostic significance of laboratory methods employed in hospitals, blood banks and physicians'' offices and with 2) scientific, administrative and clinical aspects of transfusion medicine and 3) in addition to transfusion medicine topics Clinical Laboratory represents submissions concerning tissue transplantation and hematopoietic, cellular and gene therapies.
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