评估尿道重建奖学金对地区医院尿道狭窄疾病管理的影响。

IF 1.7 3区 医学 Q4 ANDROLOGY Translational andrology and urology Pub Date : 2025-01-31 Epub Date: 2025-01-22 DOI:10.21037/tau-24-550
Clarissa M Gurbani, Bellamy Brodie, Ian Eardley, Weida Lau
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引用次数: 0

摘要

背景:在国际上,早期尿道成形术是治疗尿道狭窄的一种趋势,与内窥镜治疗相反,内窥镜治疗与短暂的通畅和频繁的再治疗有关。本研究的目的是比较通过奖学金项目获得尿道重建专业知识前后尿道狭窄治疗的结果。方法:这是一项回顾性病例对照研究,比较了连续两段时间——奖学金前(2016年9月至2019年9月)和奖学金后(2019年10月至2022年9月)治疗尿道狭窄疾病的特征、治疗和结果。结果:奖学金前组37例,奖学金后组30例。在治疗选择方面,接受指数尿道成形术的患者比例从2.7%显著增加到36.7%[优势比(OR) 18.9, 95%可信区间(CI): 2.7 ~ 209.8,比值比(pv) 16.7%, OR 2.99, 95% CI: 1.6 ~ 5.9, P=0.001)。每位患者的平均手术次数也有所减少(1.65±0.98比1.23±0.63,P=0.04)。此外,与奖学金前组相比,奖学金后6个月的总体通畅率有改善的趋势。结论:本研究表明,尿道重建专业知识与尿道狭窄患者接受尿道成形术的风险增加有关,尿道成形术是一种更有效的手术,并且与降低的再治疗率有关。这些专业知识可以为患者和区域机构带来成本效益。
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Evaluating the impact of a urethral reconstruction fellowship on urethral stricture disease management at a regional hospital.

Background: Internationally, there is a trend towards early urethroplasty for treatment of urethral stricture, as opposed to endoscopic management, which is associated with short-lived patency and frequent retreatments. The objective of this study was to compare the outcomes of urethral stricture management before and after gaining urethral reconstruction expertise through a fellowship programme.

Methods: This was a retrospective case-control study that compared the characteristics, management, and outcomes of urethral stricture disease managed over two consecutive periods of time-pre-fellowship period (September 2016 to September 2019) and the post-fellowship period (October 2019 to September 2022).

Results: There were 37 patients in the pre-fellowship group and 30 patients in the post-fellowship group. Regarding treatment choice, the proportion of patients undergoing index urethroplasty significantly increased from 2.7% to 36.7% [odds ratio (OR) 18.9, 95% confidence interval (CI): 2.7 to 209.8, P<0.008], due to early recognition of strictures not amenable endoscopic treatment. Retreatment became less frequent post-fellowship (37.8% vs. 16.7%, OR 2.99, 95% CI: 1.6 to 5.9, P=0.001). Average number of procedures per patient also reduced (1.65±0.98 vs. 1.23±0.63, P=0.04). Also, there was a trend towards improved overall patency rate at 6-month in the post-fellowship period compared to the pre-fellowship group.

Conclusions: This study has demonstrated that urethral reconstruction expertise was correlated to the increased exposure of urethral stricture patients to urethroplasty as a more efficacious procedure, and was associated with reduced retreatment rates. The expertise can bring cost benefits for patients and regional institutions.

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来源期刊
CiteScore
4.10
自引率
5.00%
发文量
80
期刊介绍: ranslational Andrology and Urology (Print ISSN 2223-4683; Online ISSN 2223-4691; Transl Androl Urol; TAU) is an open access, peer-reviewed, bi-monthly journal (quarterly published from Mar.2012 - Dec. 2014). The main focus of the journal is to describe new findings in the field of translational research of Andrology and Urology, provides current and practical information on basic research and clinical investigations of Andrology and Urology. Specific areas of interest include, but not limited to, molecular study, pathology, biology and technical advances related to andrology and urology. Topics cover range from evaluation, prevention, diagnosis, therapy, prognosis, rehabilitation and future challenges to urology and andrology. Contributions pertinent to urology and andrology are also included from related fields such as public health, basic sciences, education, sociology, and nursing.
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