2型糖尿病管理的4种循证营养选择

IF 5.4 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM Journal of Clinical Endocrinology & Metabolism Pub Date : 2025-02-25 DOI:10.1210/clinem/dgae646
Revital Gorodeski Baskin, Kimberly A Karp
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引用次数: 0

摘要

背景:2型糖尿病是一种复杂、普遍的疾病,造成健康和经济负担。目标是阻止胰岛素需求的发展,饮食改变已被认为是治疗方案中的一线干预措施。回顾了四种基于证据的营养选择及其对代谢后果的益处。证据获取:我们使用PubMed数据库对相关文献进行了全面搜索,包括最近的系统综述、荟萃分析和原始研究文章。证据综合:地中海和植物性饮食已被证明对预防和治疗糖尿病、减轻体重、改善血脂和降低整体心血管风险有好处。低碳水化合物饮食是降低血红蛋白A1c (HbA1c)的另一个可行选择,尽管它没有统一的定义,而且很难长期维持。生酮饮食同样是非常严格的,并产生显著的HbA1c降低。结论:2型糖尿病是一种广泛存在的疾病,预防和治疗至关重要。第一线的治疗是生活方式的改变,饮食干预是最重要的。凭借独特的临床模式和多种饮食选择,我们的项目致力于个性化的循证护理。营养调整是克服胰岛素抵抗和高胰岛素血症的最佳初始方法。所有的饮食调整,就像任何医疗干预一样,都需要对其利弊进行教育。
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Navigating the Spectrum of 4 Evidence-Based Nutrition Options for Type 2 Diabetes Management.

Context: Type 2 diabetes mellitus is a complex, pervasive disease that creates a health and financial burden. The goal is to head off progression to insulin requirement, and dietary changes have been recognized as a first-line intervention in the treatment protocol. Four evidence-based nutritional options are reviewed and their benefits for metabolic consequences.

Evidence acquisition: We conducted a comprehensive search of relevant literature using the PubMed database for recent systematic reviews, meta-analyses, and original research articles.

Evidence synthesis: The Mediterranean and plant-based diets have demonstrated benefits for the prevention and treatment of diabetes, weight reduction, lipid improvements, and overall cardiovascular risk reduction. A low carbohydrate diet is another viable option for hemoglobin A1c (HbA1c) reduction, though it is not as uniformly defined and is difficult to maintain long term. The ketogenic diet is similarly very restrictive and produces significant HbA1c reductions.

Conclusion: Type 2 diabetes prevention and treatment is crucial in this widespread disease. The first-line treatment is lifestyle modifications with dietary interventions being at the forefront. With a unique clinical model and a variety of dietary options, our program strives for individualized evidence-based care. Nutritional modifications are the best initial approaches to overcoming insulin resistance and hyperinsulinemia. All dietary modifications, like any medical intervention, require education on benefits vs risks.

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来源期刊
Journal of Clinical Endocrinology & Metabolism
Journal of Clinical Endocrinology & Metabolism 医学-内分泌学与代谢
CiteScore
11.40
自引率
5.20%
发文量
673
审稿时长
1 months
期刊介绍: The Journal of Clinical Endocrinology & Metabolism is the world"s leading peer-reviewed journal for endocrine clinical research and cutting edge clinical practice reviews. Each issue provides the latest in-depth coverage of new developments enhancing our understanding, diagnosis and treatment of endocrine and metabolic disorders. Regular features of special interest to endocrine consultants include clinical trials, clinical reviews, clinical practice guidelines, case seminars, and controversies in clinical endocrinology, as well as original reports of the most important advances in patient-oriented endocrine and metabolic research. According to the latest Thomson Reuters Journal Citation Report, JCE&M articles were cited 64,185 times in 2008.
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