三瓣手术后生存的预测因素:单中心分析

Jennie Hocking MPAS , John B. Eisenga MD , Austin Kluis MD , Kyle A. McCullough MD , Ghadi Moubarak MD , J. Michael DiMaio MD , William Ryan MD
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摘要

背景:三瓣手术是一项复杂的手术,围手术期死亡率高。关于该手术成功的预测因素的数据有限。我们报告我们的经验。方法2007年11月至2022年7月在1家医院接受三瓣手术的211例患者。回顾了基线特征、手术细节和死亡率结果。结果重做手术82例(38.9%),紧急手术68例(32.2%)。通常,主动脉(n = 194;91.4%)和二尖瓣(n = 140;66.4%)瓣膜置换术,三尖瓣(n = 189;89.6%)修理。28%的患者接受了伴随手术。211例患者中30天死亡率为21例(9.95%)。1年和7年Kaplan-Meyer生存率分别为86.0%(四分位数范围79%-93%)和64.0%(四分位数范围55%-74%)。多因素回归分析,终末期肾病(风险比4.16;P = 0.003)与死亡率和二尖瓣置换术相关(风险比,0.44;P = 0.009)与改善的长期生存相关。结论:尽管有大量的重做和伴随手术,我们报告30天死亡率低于10%,1年生存率为86%。在我们的研究中,二尖瓣置换术对长期生存有好处。
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Predictors of Survival After Triple Valve Surgery: A Single Center Analysis

Background

Triple valve surgery is a complex operation with high perioperative mortality. Limited data exist regarding the predictors of success associated with this surgery. We report our experience.

Methods

A total of 211 sequential patients underwent triple valve surgery at 1 hospital from November 2007 through July 2022. Baseline characteristics, operative details, and mortality outcomes were reviewed.

Results

Eighty-two (38.9%) were redo operations and 68 (32.2%) were urgent. Commonly, aortic (n = 194; 91.4%) and mitral (n = 140; 66.4%) valves were replaced, and the tricuspid valve (n = 189; 89.6%) repaired. Concomitant procedures were done in 28% of patients. Thirty-day mortality was 21 of 211 (9.95%). Kaplan-Meyer survival at 1 and 7 years was 86.0% (interquartile range, 79%-93%) and 64.0% (interquartile range, 55%-74%), respectively. On multivariate regression, end-stage renal disease (hazard ratio, 4.16; P = .003) was associated with mortality, and mitral valve replacement (hazard ratio, 0.44; P = .009) was associated with improved long-term survival.

Conclusions

Despite the high number of redo and concomitant procedures, we report a 30-day mortality rate under 10% and an 86% 1-year survival. In our series, mitral valve replacement conferred a long-term survival benefit.
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