多灶性棕色肿瘤1例报告并文献复习。

IF 1.5 The journal of medicine access Pub Date : 2025-02-24 eCollection Date: 2025-01-01 DOI:10.1177/27550834251322005
Mainak Roy, Samir Dwidmuthe
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引用次数: 0

摘要

棕色肿瘤虽然罕见,但却是甲状旁腺功能亢进的重要表现,常表现为多灶性溶骨病变,偶尔导致病理性骨折。本病例报告详细介绍了一位38岁男性多灶性棕色肿瘤的表现和治疗,包括右胫骨骨折,并提供了全面的文献回顾。患者表现为腿部、大腿和前臂多发溶骨性病变,同时血清钙和甲状旁腺激素(PTH)水平升高。治疗包括保守骨折治疗、手术切除甲状旁腺瘤和术后康复。随访显示胫骨骨折愈合显著,溶骨病灶大小减小。本报告强调了及时诊断和综合治疗对于预防并发症和改善多灶性棕色肿瘤患者预后的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Multifocal brown tumors: A case report and literature review.

Brown tumors, though rare, are significant manifestations of hyperparathyroidism, often presenting with multifocal osteolytic lesions and occasionally leading to pathological fractures. This case report details the presentation and management of a 38-year-old male with multifocal brown tumors, including a right tibial fracture, and provides a comprehensive literature review. The patient exhibited multiple osteolytic lesions in the legs, thighs, and forearms, alongside elevated serum calcium and parathyroid hormone (PTH) levels. Management included conservative fracture treatment, surgical resection of the parathyroid adenoma, and postoperative rehabilitation. Follow-up revealed significant tibial fracture healing and reduction in the size of osteolytic lesions. This report underscores the importance of timely diagnosis and comprehensive management to prevent complications and improve outcomes in patients with multifocal brown tumors.

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