免疫缺陷患者的慢性诺如病毒感染:英国全国病例系列。

Alexandros Grammatikos, Anisha Mangtani, Mark Ponsford, Stephen Jolles, Elizabeth McDermott, Sarah Johnston, Marina Frleta-Gilchrist, Patrick Yong, Fiona Moghaddas, Moira Thomas, Smita Patel, Caitlin Blundell, Phil Bright, Elizabeth Drewe, Suzanne Elcombe, Archana Herwadkar, Sai Murng, Da-In Kim, Mark Gompels, David Lowe
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引用次数: 0

摘要

临床意义:慢性诺如病毒感染可导致免疫缺陷患者严重腹泻、吸收不良和体重减轻。这些患者的临床和组织学表现非常相似,表明病毒是肠病的主要驱动因素。
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Chronic norovirus infection in immunodeficiency: a UK national case series.

Clinical implications: Chronic norovirus infection can lead to significant diarrhoea, malabsorption, and weight loss in immunodeficiency. The clinical and histological picture in these patients is remarkably similar, suggesting that the virus is a main driver for the enteropathy.

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来源期刊
CiteScore
11.10
自引率
9.60%
发文量
683
审稿时长
50 days
期刊介绍: JACI: In Practice is an official publication of the American Academy of Allergy, Asthma & Immunology (AAAAI). It is a companion title to The Journal of Allergy and Clinical Immunology, and it aims to provide timely clinical papers, case reports, and management recommendations to clinical allergists and other physicians dealing with allergic and immunologic diseases in their practice. The mission of JACI: In Practice is to offer valid and impactful information that supports evidence-based clinical decisions in the diagnosis and management of asthma, allergies, immunologic conditions, and related diseases. This journal publishes articles on various conditions treated by allergist-immunologists, including food allergy, respiratory disorders (such as asthma, rhinitis, nasal polyps, sinusitis, cough, ABPA, and hypersensitivity pneumonitis), drug allergy, insect sting allergy, anaphylaxis, dermatologic disorders (such as atopic dermatitis, contact dermatitis, urticaria, angioedema, and HAE), immunodeficiency, autoinflammatory syndromes, eosinophilic disorders, and mast cell disorders. The focus of the journal is on providing cutting-edge clinical information that practitioners can use in their everyday practice or to acquire new knowledge and skills for the benefit of their patients. However, mechanistic or translational studies without immediate or near future clinical relevance, as well as animal studies, are not within the scope of the journal.
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