Bohdan Biletskyi, Maxime Dousset, Pierre Colonna, Virginie Héran, Yannick Carissan, Laurent Commeiras, Gaëlle Chouraqui
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Formation of Substituted Benzocyclobutenes Starting from Donor–Acceptor Cyclopropanes
We describe an operationally simple, good-yielding, two-step cascade process to convert biscyclopropanes 1 into high-value benzocyclobutene building blocks 3. This study highlights the novel reactivity of our “in-house” donor–acceptor cyclopropane, achieving complete diastereoselectivity and regioselectivity transfer.
期刊介绍：
Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.
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