{"title":"吡啶衍生的1,2,3-三唑基有机硅烷作为Zn（II）离子的“开启”荧光传感器：合成、抗氧化、分子对接和DFT研究","authors":"Gurjaspreet Singh, Komal, Anu Radha, Jigmat Stanzin, Jyoti, Vinit Yadav, Amarjit Kaur","doi":"10.1002/aoc.70114","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>The article emphasises the synthesis of pyrrolidine-derived 1,2,3-triazolyl organosilane 5 which was well characterised by utilising spectroscopic techniques such as NMR (<sup>1</sup>H and <sup>13</sup>C), IR, elemental analysis, UV–visible, fluorescence and mass spectrometry. The molecule exhibits exceptional sensitivity to Zn<sup>2+</sup> in comparison to other ions, which is demonstrated by fluorescence spectroscopy and UV–visible and with detection limits of 3.622 × 10<sup>−7</sup> and 1.893 × 10<sup>−7</sup> M, respectively. The binding stoichiometry comes out to be 1:1 by using Job's plot approach and accordingly metal–ligand complex was synthesised and then characterised. Further, the molecule exhibits notable antioxidant property examined with DPPH assay. ‘Molecular docking’ was used to determine the binding interactions of molecule with superoxide dismutase (SOD) (PDB ID-1Z9P).</p>\n </div>","PeriodicalId":8344,"journal":{"name":"Applied Organometallic Chemistry","volume":"39 4","pages":""},"PeriodicalIF":4.3000,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pyrrolidine-Derived 1,2,3-Triazolyl Organosilane as ‘Turn-On’ Fluorescence Sensor for Zn(II) Ion: Synthesis, Antioxidant, Molecular Docking and DFT Studies\",\"authors\":\"Gurjaspreet Singh, Komal, Anu Radha, Jigmat Stanzin, Jyoti, Vinit Yadav, Amarjit Kaur\",\"doi\":\"10.1002/aoc.70114\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <p>The article emphasises the synthesis of pyrrolidine-derived 1,2,3-triazolyl organosilane 5 which was well characterised by utilising spectroscopic techniques such as NMR (<sup>1</sup>H and <sup>13</sup>C), IR, elemental analysis, UV–visible, fluorescence and mass spectrometry. The molecule exhibits exceptional sensitivity to Zn<sup>2+</sup> in comparison to other ions, which is demonstrated by fluorescence spectroscopy and UV–visible and with detection limits of 3.622 × 10<sup>−7</sup> and 1.893 × 10<sup>−7</sup> M, respectively. The binding stoichiometry comes out to be 1:1 by using Job's plot approach and accordingly metal–ligand complex was synthesised and then characterised. Further, the molecule exhibits notable antioxidant property examined with DPPH assay. ‘Molecular docking’ was used to determine the binding interactions of molecule with superoxide dismutase (SOD) (PDB ID-1Z9P).</p>\\n </div>\",\"PeriodicalId\":8344,\"journal\":{\"name\":\"Applied Organometallic Chemistry\",\"volume\":\"39 4\",\"pages\":\"\"},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2025-03-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied Organometallic Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/aoc.70114\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Organometallic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/aoc.70114","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
Pyrrolidine-Derived 1,2,3-Triazolyl Organosilane as ‘Turn-On’ Fluorescence Sensor for Zn(II) Ion: Synthesis, Antioxidant, Molecular Docking and DFT Studies
The article emphasises the synthesis of pyrrolidine-derived 1,2,3-triazolyl organosilane 5 which was well characterised by utilising spectroscopic techniques such as NMR (1H and 13C), IR, elemental analysis, UV–visible, fluorescence and mass spectrometry. The molecule exhibits exceptional sensitivity to Zn2+ in comparison to other ions, which is demonstrated by fluorescence spectroscopy and UV–visible and with detection limits of 3.622 × 10−7 and 1.893 × 10−7 M, respectively. The binding stoichiometry comes out to be 1:1 by using Job's plot approach and accordingly metal–ligand complex was synthesised and then characterised. Further, the molecule exhibits notable antioxidant property examined with DPPH assay. ‘Molecular docking’ was used to determine the binding interactions of molecule with superoxide dismutase (SOD) (PDB ID-1Z9P).
期刊介绍：
All new compounds should be satisfactorily identified and proof of their structure given according to generally accepted standards. Structural reports, such as papers exclusively dealing with synthesis and characterization, analytical techniques, or X-ray diffraction studies of metal-organic or organometallic compounds will not be considered. The editors reserve the right to refuse without peer review any manuscript that does not comply with the aims and scope of the journal. Applied Organometallic Chemistry publishes Full Papers, Reviews, Mini Reviews and Communications of scientific research in all areas of organometallic and metal-organic chemistry involving main group metals, transition metals, lanthanides and actinides. All contributions should contain an explicit application of novel compounds, for instance in materials science, nano science, catalysis, chemical vapour deposition, metal-mediated organic synthesis, polymers, bio-organometallics, metallo-therapy, metallo-diagnostics and medicine. Reviews of books covering aspects of the fields of focus are also published.
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