Boron Ester compounds as daily food supplements

In recent years, with the increasing popularity of complementary and alternative therapies worldwide, interest in dietary supplements has also begun to rise. It is known that boron is effective in energy, mineral, hormone, bone, and skeletal metabolism. It is accepted that it has a regulatory function in maintaining various other biological processes. The chemical state of boron is very important in nutrition. In plants, boron is found in the form of sugar esters. Boron sugar esters are the best chemical form for assimilation by cells. It is necessary to emphasize and enhance the positive effects of boron on cells by obtaining complex structures with -OBO- ester bonds. It has been observed that the boron compounds in these foods are "boron ester derivatives". There are specific biochemical, preclinical, and clinical studies investigating the dietary intake of boron ester derivatives. However, studies on the synthesis and structural characterization of boron esters are more limited. Within the scope of this study, the synthesis, structural characterization, and various application studies of borate compounds examined by our group and different researchers have been compiled. By researching the synthesis and structural characterization of borate esters, we believe we will contribute to the literature on these compounds, which are known to be promising for a healthy life.