YL-1血肿粉碎针联合血肿引流治疗脑出血疗效观察。

IF 3.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Frontiers in Medicine Pub Date : 2025-02-26 eCollection Date: 2025-01-01 DOI:10.3389/fmed.2025.1495160
Xianyong Chen, Danhong Chen, Shaonan Sun, Zhenyong Huang, Weipeng Hu, Qiangbin Zhu
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摘要

目的:血肿手术早期开颅引流对自发性脑出血(ICH)患者的预后无明显改善。YL-1血肿粉碎穿刺针是专为脑出血清除设计的,治疗效果不确定。本研究旨在评价其临床疗效。材料和方法:我们回顾性分析了2016年9月至2023年3月在我院行扭转骨内钻针(TIDN)手术的脑出血患者的病历。分析临床结果。结果:手术组血肿消退时间明显短于保守组,平均缩短14.71天(p < 0.001)。手术组Barthel指数改善明显,平均提高8.214点(p < 0.001)。入院后7天,手术组格拉斯哥昏迷评分(GCS)评分的提高明显高于手术组,平均提高1.471分(p < 0.001)。此外,手术组甘露醇给药时间显著缩短(p < 0.001)。结论:TIDN联合血肿引流是治疗基底神经节出血的一种可行的手术选择。这种方法似乎减少了甘露醇的使用,减轻了开颅相关的风险,并促进了GCS评分和Barthel指数的短期改善,突出了其潜在的临床益处。
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Efficacy of YL-1 hematoma crushing needle combined with hematoma drainage in intracerebral hemorrhage treatment.

Objective: Early craniotomy evacuation in hematoma surgery does not significantly improve the prognosis of patients with spontaneous intracerebral hemorrhage (ICH). The YL-1 hematoma crushing puncture needle, specifically designed for ICH evacuation, has an uncertain therapeutic efficacy. This study aimed to evaluate its clinical effectiveness.

Materials and methods: We retrospectively reviewed medical records of patients with ICH who underwent twist intraosseous drill needle (TIDN) surgery at our institution between September 2016 and March 2023. Clinical outcomes were analyzed.

Results: The surgical group demonstrated a significantly shorter hematoma resolution time, averaging 14.71 days less than the conservative group (p < 0.001). The Barthel Index improved more in the surgical group, with an average increase of 8.214 points (p < 0.001). Seven days post-admission, the increase in Glasgow Coma Scale (GCS) scores was significantly higher in the surgical group, with an average improvement of 1.471 points (p < 0.001). Additionally, the duration of mannitol administration was significantly reduced in the surgical group (p < 0.001).

Conclusion: TIDN surgery combined with hematoma drainage may serve as a viable surgical alternative for basal ganglia hemorrhage patients. This approach appears to reduce mannitol usage, mitigate craniotomy-associated risks, and promote short-term improvements in GCS scores and Barthel Index, highlighting its potential clinical benefits.

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来源期刊
Frontiers in Medicine
Frontiers in Medicine Medicine-General Medicine
CiteScore
5.10
自引率
5.10%
发文量
3710
审稿时长
12 weeks
期刊介绍: Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate - the use of patient-reported outcomes under real world conditions - the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines - the scientific bases for guidelines and decisions from regulatory authorities - access to medicinal products and medical devices worldwide - addressing the grand health challenges around the world
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