木瓜籽粘液对会阴切开术后会阴疼痛和愈合的影响:一项随机、三盲、安慰剂对照研究。

IF 4.3 3区 医学 Q2 CELL BIOLOGY Wound Repair and Regeneration Pub Date : 2025-03-01 DOI:10.1111/wrr.70012
Foruzan Sharifipour, Nader Salari, Nasim Jamshidi, Zahra Javanbakht, Faeze Azizi, Shahla Faal Siahkal
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引用次数: 0

摘要

据报道,会阴切开术在伊朗的发生率很高,导致会阴感染和疼痛等并发症。本研究探讨了榅桲籽粘液对会阴疼痛愈合过程的影响。一项三盲临床试验于2023年10月至2024年8月在伊朗进行,涉及90名初产妇女,她们被随机分配到昆斯凝胶组或安慰剂组,持续14天,每天给药三次。主要结局包括伤口愈合和疼痛,采用REEDA问卷和视觉模拟量表进行评估。数据分析采用SPSS版本25。修复后即刻的REEDA和VAS评分组间差异无统计学意义(p < 0.05)。然而,在第14天,总体REEDA和VAS评分显示,干预组的伤口愈合和疼痛水平明显优于对照组(p = 0.001 vs. p = 0.002)。本研究证实了木瓜黏液在促进伤口愈合和减轻疼痛方面的有益作用。这种粘液的应用可以促进母亲更快地恢复正常。
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The effect of quince seed mucilage on perineal pain and healing following episiotomy: A randomised, triple-blind, placebo-controlled study.

The incidence of episiotomy in Iran has been reported to be high, resulting in complications such as perineal infection and pain. This study investigates the effects of quince seed mucilage on the healing process and perineal pain. A triple-blinded clinical trial was conducted from October 2023 to August 2024 in Iran, involving 90 primiparous women who were randomly assigned to either the quince gel group or the placebo group for a duration of 14 days, with administration three times daily. The primary outcomes included wound healing and pain, which were evaluated using the REEDA questionnaire and the visual analogue scale. Data analysis was performed utilising SPSS version 25. There were no statistically significant differences found between the groups regarding the REEDA and VAS scores immediately following repair (p > 0.05). However, on day 14, the overall REEDA and VAS scores indicated that wound healing and pain levels in the intervention group were significantly more favourable than those in the control group (p = 0.001 vs. p = 0.002, respectively). This study demonstrates the beneficial impact of quince mucilage on improving wound healing and alleviating pain. The application of this mucilage may facilitate a quicker return to normalcy for mothers.

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来源期刊
Wound Repair and Regeneration
Wound Repair and Regeneration 医学-皮肤病学
CiteScore
5.90
自引率
3.40%
发文量
71
审稿时长
6-12 weeks
期刊介绍: Wound Repair and Regeneration provides extensive international coverage of cellular and molecular biology, connective tissue, and biological mediator studies in the field of tissue repair and regeneration and serves a diverse audience of surgeons, plastic surgeons, dermatologists, biochemists, cell biologists, and others. Wound Repair and Regeneration is the official journal of The Wound Healing Society, The European Tissue Repair Society, The Japanese Society for Wound Healing, and The Australian Wound Management Association.
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