未来就是现在:在帕金森氏症和前驱疾病的疾病改善试验的澳大利亚观点。

IF 2.4 Q3 CLINICAL NEUROLOGY BMJ Neurology Open Pub Date : 2025-03-21 eCollection Date: 2025-01-01 DOI:10.1136/bmjno-2025-001070
Simon Jg Lewis, Carolyn M Sue, Antony Cooper, Glenda M Halliday
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引用次数: 0

摘要

人们对平台试验的作用越来越感兴趣,在平台试验中,可以同时评估几种针对帕金森病疾病改变的研究产品。事实上,北美和欧洲目前正在加紧开展几项举措,以进行此类研究。然而,迄今为止,人们很少关注澳大利亚正在进行的努力,这些努力已经在澳大利亚开展,并有望很快扩展到新西兰,成为更广泛合作的一部分。本报告将重点介绍其中一些正在进行的工作,探讨成功开展研究所面临的挑战和可能的解决方案。
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Future is now: an Australasian perspective on disease-modifying trials in Parkinson's and prodromal disease.

There is increasing interest in the role of platform trials, where several investigational products targeting disease modification in Parkinson's Disease can be assessed in parallel. Indeed, several initiatives are currently gearing up across North America and Europe to conduct such studies. However, to date, little attention has been paid to ongoing efforts that already exist in Australia and look soon to expand across to New Zealand as part of greater collaboration. This viewpoint will highlight some of these ongoing efforts addressing the challenges and potential solutions for delivering successful studies.

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来源期刊
BMJ Neurology Open
BMJ Neurology Open Medicine-Neurology (clinical)
CiteScore
3.20
自引率
3.70%
发文量
46
审稿时长
13 weeks
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