外伤性视神经病变的诊断与治疗。

R E Frenkel, T C Spoor
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引用次数: 0

摘要

如果患者在外伤后立即恢复视力,随后视力和/或视野恶化,并且存在相对传入瞳孔缺损,视神经或其血管供应很可能受到压迫。我们目前缺乏一种经证实的最佳治疗方法,但对于其他方面健康的患者,我们建议静脉注射(IV)负荷剂量的甲基强的松龙30mg /kg,在初始剂量后2小时第二次给药15mg /kg,随后每6小时给药15mg /kg。视神经减压是指在这种情况下,皮质类固醇只有一个暂时的作用,一个逐渐减弱,或根本没有。当有外伤性视神经病变伴视神经孔骨折或狭窄或骨碎片脱位直接冲击神经时,也可进行检查。视神经鞘减压术适用于进行性外伤性视神经病变,超声检查显示视神经鞘增大,充满液体。
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Diagnosis and management of traumatic optic neuropathies.

If a patient has vision immediately following trauma, with subsequent deterioration of visual acuity and/or field, and the presence of a relative afferent pupillary defect, compression of the optic nerve or its vascular supply is very likely. We currently lack a proven optimal treatment, but in the otherwise healthy patient, we suggest an intravenous (IV) loading dose of methylprednisolone 30 mg/kg, and a second 15-mg/kg dose 2 hours after the initial dose, followed by 15 mg/kg every 6 hours. Optic nerve decompression is indicated in this situation when corticosteroids have only a temporary effect, a diminishing one, or none at all. It may also be indicated when there is evidence of a traumatic optic neuropathy with a fractured or narrowed optic foramen or with dislocated bone fragments that directly impinge on the nerve. Optic nerve sheath decompression is indicated in progressive traumatic optic neuropathy when an enlarged fluid-filled sheath has been demonstrated sonographically.

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