ALAN J. ZAMETKIN M.D., JAN C. REEVES M.B., CH.B., LOUISE WEBSTER M.B., CH.B., JOHN S. WERRY M.D.
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Promethazine Treatment of Children with Attention Deficit Disorder with Hyperactivity—Ineffective and Unpleasant
Eight children with Attention Deficit Disorder with Hyperactivity were treated with methylphenidate and promethazine in an open crossover design study. No improvement occurred with promethazine, while behavioral deterioration in four subjects necessitated discontinuation of the drug in two cases.