大鼠触须真皮乳头诱导小鼠皮肤毛囊的研究。

P Pisansarakit, G P Moore
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引用次数: 0

摘要

将大鼠触须真皮乳头移植于离体小鼠胚皮表皮和真皮之间,然后移植到裸鼠身上。乳突诱导形成的毛囊比寄主皮肤的毛囊大,但比触须毛囊小。讨论了分离的真皮乳头诱导毛囊的潜力,这些毛囊具有乳头起源的特征。影响诱导卵泡大小的主要因素之一可能与诱导过程中乳头团的分裂和细胞通过入侵宿主皮肤的表皮细胞索而分散有关。
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Induction of hair follicles in mouse skin by rat vibrissa dermal papillae.

Rat vibrissa dermal papillae were transplanted between the epidermis and dermis of isolated embryonic mouse skin and then grafted onto nude mice. The papillae induced the formation of hair follicles which were larger than those of the host skin but smaller than vibrissa follicles. The potential of isolated dermal papillae to induce follicles with characteristics of those from which the papillae originated is discussed. One of the major factors affecting the sizes of induced follicles may have been related to the splitting of the papilla mass and dispersal of the cells by invading cords of epidermal cells from the host skin during induction.

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