角膜试验是检测小鼠迟发性超敏反应的可靠方法。

Biken journal Pub Date : 1987-03-01

I Morisaki, T Shimono, N Kohno, D E Stewart-Tull, S Kotani, H Kitamura

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引用次数: 0

摘要

抗原溶液可以用细针和立体解剖显微镜注射到致敏小鼠的角膜内。结果表明，用含有卵清蛋白和细胞壁佐剂的油包水乳剂免疫小鼠后，角膜反应是检测和估计迟发性超敏反应的可靠方法。与耳垂的延迟皮肤反应不同，这种角膜反应不受共存的Arthus反应的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Corneal test as a reliable method for detection of the delayed-type hypersensitivity reaction in mice.

Antigen solution could be injected into the cornea of sensitized mice using a fine needle and a stereoscopic dissecting microscope. The resulting corneal reaction was shown to be a reliable method in the detection and estimation of delayed-type hypersensitivity in mice that had been immunized with a water-in-oil emulsion containing an ovalbumin and a cell wall adjuvant. Unlike the delayed skin reaction in the ear lobe, this corneal reaction was not affected by a coexisting Arthus reaction.

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Biken journal

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