性早熟的生物行为方面

WILLIAM A. SONIS M.D., FLORENCE COMITE M.D., ORA H. PESCOVITZ M.D., KAREN HENCH R.N., CHARLES W. RAHN M.S.W., GORDON B. CUTLER Jr. M.D., D L LORIAUX M.D., Ph.D., ROBERT P. KLEIN Ph.D.
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引用次数: 16

摘要

性早熟是自然界的一个实验,从中我们可以了解早期和持续接触性类固醇对人类行为的影响。我们研究了77例性早熟儿童的行为问题、脑损伤、身高和两种性类固醇暴露之间的关系。使用儿童行为检查表评估行为问题。我们发现,无论病因如何,性早熟的诊断都是增加行为问题的危险因素。尽管可能存在与环境和心理变量相关的重要影响,但我们发现,患有特发性性早熟的年龄较大的女孩,与同龄人的预期身高更接近,阴毛更少,有更多的行为问题。
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Biobehavioral Aspects of Precocious Puberty

Precocious puberty is an experiment in nature from which we can learn about the effects of early and continuous exposure to sex steroids on human behavior. We studied the relationships between behavior problems, brain lesions, height, and two measures of sex steroid exposure in 77 children with precocious puberty. Behavior problems were assessed using the Child Behavior Checklist. We found that the diagnosis of precocious puberty regardless of the etiology was a risk factor for increased behavior problems. Although there may be important effects related to environmental and psychological variables, we found that older girls with idiopathic precocious puberty who looked closer to expected peer height and who had less pubic hair had more behavior problems.

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