The importance of separation anxiety in the differentiation of panic disorder from agoraphobia.

When patients with panic disorders are divided into two groups, those that are without any signs of phobic avoidance and those that are frankly agoraphobic, we see a differential premorbid history of separation anxiety in childhood with school phobia. The former group we found to be without these problems, while the latter demonstrated a history of school phobia in the majority of cases (60 per cent). This may indicate that uncomplicated panic disorder and agoraphobia with panic attacks are not always differential cross-sections of the same disease process, or different levels of severity of the same psychopathological entity, but may represent illnesses best not conceptualized as lying on a continuum. Further research will be served by separating panic disorder (DSM-III 300.01) into two groups: uncomplicated panic disorder, and panic disorder with limited phobic avoidance, which will exist along with the present agoraphobia with panic attacks, perhaps best renamed panic disorder with extensive phobic avoidance.