血液透析过程中超敏反应的机制。

Transactions - American Society for Artificial Internal Organs Pub Date : 1985-01-01

H D Lemke, F Kuentz, M Forêt

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摘要

我们认为透析期间许多严重的超敏反应是IgE介导的(经典过敏反应)。除了ETO外，还必须涉及其他不能从透析器中提取的物质(例如肝素)。一些严重的反应不能用血清中的高IgE水平来解释。然而，体外补体激活并没有显示过敏毒素介导的反应机制，至少在严重的过敏病例中是如此。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Mechanisms of hypersensitivity reactions during hemodialysis.

We suggest that many severe hypersensitivity reactions during dialysis are IgE mediated (classical anaphylaxis). Besides ETO there must be other substances involved which are not extractable from the dialyzer (e.g. heparin). Some severe reactions are not explained by high IgE levels in the serum. However, in vitro complement activation gives no indication of an anaphylatoxin mediated reaction mechanism, at least in the severe cases of hypersensitivity.

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Transactions - American Society for Artificial Internal Organs

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