黑麦中较高含量的醇同系物(5-烯基间苯二酚)影响红细胞膜-水运输。

A Kozubek
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引用次数: 10

摘要

采用300 mM蔗糖渗透收缩实验,研究了从黑麦颗粒中分离的5-庚十二基间苯二酚和总黑麦5-烯基间苯二酚对红细胞透水性的影响。所研究的化合物诱导红细胞水渗透性显著增加。提高透水性所需的阈值浓度约为10(-6)mol/l。所观察到的过程的温度依赖性表现为不连续性,这与5-烯基间苯二酚的转变温度有关。研究还表明,烯基间苯二酚对水溶性表面活性剂所观察到的红细胞低渗溶解没有双相作用。假定所研究的化合物具有特定的赖氨酸活性。
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Higher cardol homologues (5-alkenylresorcinols) from rye affect the red cell membrane-water transport.

The influence of 5-heptadecenylresorcinol and total rye 5-alkenylresorcinols isolated from rye grains on the red blood cell water permeability was studied using osmotic shrinkage experiments performed in 300 mM sucrose. The studied compounds induced significant increase of erythrocyte water permeability. The threshold concentration needed for the increase of water permeability was in an order of 10(-6) mol/l. The temperature dependence of the observed process showed the discontinuity which was related to the 5-alkenylresorcinol transition temperatures. It was shown also that alkenylresorcinols did not exert the biphasic action on hypotonic lysis of erythrocytes usually observed for water soluble surfactants. The specific lysine activity is postulated for the studied compounds.

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