Fructosylvaline。人血红蛋白A1c n端残基的简单模型。

Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry Pub Date : 1985-01-01 DOI:10.3891/acta.chem.scand.39b-0191

P Keil, H B Mortensen, C Christophersen

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引用次数: 32

摘要

合成了N-[d -果糖-(1)]- l-缬氨酸的苯腙(1-脱氧- l-缬氨酸-d -果糖)。该腙在碱性溶液中以开放形式存在，在酸性溶液中以封闭形式存在。这些发现与讨论人血红蛋白A1c与苯肼的反应有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Fructosylvaline. A simple model of the N-terminal residue of human haemoglobin A1c.

The phenylhydrazone of N-[D-fructosyl-(1)]-L-valine (1-deoxy-L-valine-D-fructose) was synthesized. The hydrazone was shown to exist in open form in basic solution and in closed form in acidic solution. The findings have bearings upon the discussion of the reaction of human haemoglobin A1c with phenylhydrazine.

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Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry

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